SNP Detail For rs997781
1.Mapping Information
Human SNP ID rs997781
Human chromosome chr17
Human SNP position 69121547
Pig chromosome chr12
Pig SNP position 11428543
2.Annotation Information
PubMed ID26183928
JournalCancer Res
Linkwww.ncbi.nlm.nih.gov/pubmed/26183928
StudyImplication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
Disease/TraitMGMT methylation in smokers
Initial sample296 European ancestry individuals with MGMT methylation, 867 European ancestry individuals without MGMT methylation
Replication sample107 European and Hispanic individuals with MGMT methylation, 323 European and Hispanic individuals without MGMT methylation
Region17q24.3
Chromosome idchr17
Chromosome position69121547
Reported geneABCA6, ABCA10
Mapped geneABCA6
Upstream gene id
Downstream gene id
SNP gene ids23460
Upstream gene distance
Downstream gene distance
SNP risk allelers997781-A
SNPsrs997781
Merged
SNP id current997781
Contextintron_variant
Intergenic0
Allele frequency0.29
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta1.63
%95 Ci[1.36-1.95]
PlatformIllumina [1599980]
CNVN
Mapped traitsmoking behavior, gene methylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0006959
Study accessionGCST003031