Human SNP ID | rs997781 |
---|---|
Human chromosome | chr17 |
Human SNP position | 69121547 |
Pig chromosome | chr12 |
Pig SNP position | 11428543 |
PubMed ID | 26183928 |
---|---|
Journal | Cancer Res |
Link | www.ncbi.nlm.nih.gov/pubmed/26183928 |
Study | Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. |
Disease/Trait | MGMT methylation in smokers |
Initial sample | 296 European ancestry individuals with MGMT methylation, 867 European ancestry individuals without MGMT methylation |
Replication sample | 107 European and Hispanic individuals with MGMT methylation, 323 European and Hispanic individuals without MGMT methylation |
Region | 17q24.3 |
Chromosome id | chr17 |
Chromosome position | 69121547 |
Reported gene | ABCA6, ABCA10 |
Mapped gene | ABCA6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 23460 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs997781-A |
SNPs | rs997781 |
Merged | |
SNP id current | 997781 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.29 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | |
Or beta | 1.63 |
%95 Ci | [1.36-1.95] |
Platform | Illumina [1599980] |
CNV | N |
Mapped trait | smoking behavior, gene methylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0006959 |
Study accession | GCST003031 |