SNP Detail For rs9952762
1.Mapping Information
Human SNP ID rs9952762
Human chromosome chr18
Human SNP position 75689695
Pig chromosome chr1
Pig SNP position 164376108
2.Annotation Information
PubMed ID26031901
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/26031901
StudyGenome-wide association study of leukotriene modifier response in asthma.
Disease/TraitResponse to zileuton treatment in asthma (FEV1 change interaction)
Initial sample160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases
Replication sample149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases
Region18q23
Chromosome idchr18
Chromosome position75689695
Reported geneintergenic
Mapped geneLOC105372202 - LOC100505853
Upstream gene id105372202
Downstream gene id100505853
SNP gene ids
Upstream gene distance179723
Downstream gene distance6388
SNP risk allelers9952762-?
SNPsrs9952762
Merged
SNP id current9952762
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000005
Pvalue mlog6.30102999566398
P value text(Dominant model)
Or beta0.64
%95 Ciunit increase
PlatformIllumina [542562]
CNVN
Mapped traitFEV change measurement, response to zileuton, asthma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270
Study accessionGCST002951