Human SNP ID | rs9952762 |
---|---|
Human chromosome | chr18 |
Human SNP position | 75689695 |
Pig chromosome | chr1 |
Pig SNP position | 164376108 |
PubMed ID | 26031901 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/26031901 |
Study | Genome-wide association study of leukotriene modifier response in asthma. |
Disease/Trait | Response to zileuton treatment in asthma (FEV1 change interaction) |
Initial sample | 160 European and other ancestry zileuton-treated cases, 144 European and other ancestry placebo-controlled cases |
Replication sample | 149 European and other ancestry zileuton-treated cases, 73 European and other ancestry placebo-controlled cases |
Region | 18q23 |
Chromosome id | chr18 |
Chromosome position | 75689695 |
Reported gene | intergenic |
Mapped gene | LOC105372202 - LOC100505853 |
Upstream gene id | 105372202 |
Downstream gene id | 100505853 |
SNP gene ids | |
Upstream gene distance | 179723 |
Downstream gene distance | 6388 |
SNP risk allele | rs9952762-? |
SNPs | rs9952762 |
Merged | |
SNP id current | 9952762 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | (Dominant model) |
Or beta | 0.64 |
%95 Ci | unit increase |
Platform | Illumina [542562] |
CNV | N |
Mapped trait | FEV change measurement, response to zileuton, asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007676, http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST002951 |