Human SNP ID | rs9895661 |
---|---|
Human chromosome | chr17 |
Human SNP position | 61379228 |
Pig chromosome | chr12 |
Pig SNP position | 38360247 |
PubMed ID | 20383146 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20383146 |
Study | New loci associated with kidney function and chronic kidney disease. |
Disease/Trait | Chronic kidney disease |
Initial sample | Up to 67,093 European ancestry individuals |
Replication sample | Up to 22,982 European ancestry individuals |
Region | 17q23.2 |
Chromosome id | chr17 |
Chromosome position | 61379228 |
Reported gene | BCAS3, TBX2, C17orf82 |
Mapped gene | LOC101927855, BCAS3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101927855, 54828 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs9895661-C |
SNPs | rs9895661 |
Merged | 0 |
SNP id current | 9895661 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.000000000000001 |
Pvalue mlog | 15 |
P value text | (eGFRcrea) |
Or beta | 0.01 |
%95 Ci | [0.007-0.015] ml/min/1.73 m2 decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | chronic kidney disease, serum creatinine measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0004518 |
Study accession | GCST000649 |
PubMed ID | 22797727 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22797727 |
Study | Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Disease/Trait | Renal function-related traits (sCR) |
Initial sample | 42,257 East Asian, South Asian, and South East Asian ancestry individuals |
Replication sample | 19,662 East Asian ancestry individuals |
Region | 17q23.2 |
Chromosome id | chr17 |
Chromosome position | 61379228 |
Reported gene | BCAS3 |
Mapped gene | LOC101927855, BCAS3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101927855, 54828 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs9895661-C |
SNPs | rs9895661 |
Merged | 0 |
SNP id current | 9895661 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.52 |
P value | 0.00000000007 |
Pvalue mlog | 10.1549019599857 |
P value text | |
Or beta | 0.0045 |
%95 Ci | [0.0031-0.0059] mg/dl increase |
Platform | Affymetrix, Illumina [2353587] (imputed) |
CNV | N |
Mapped trait | renal system measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742 |
Study accession | GCST001606 |
PubMed ID | 22797727 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22797727 |
Study | Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Disease/Trait | Renal function-related traits (eGRFcrea) |
Initial sample | 42,451 East Asian, South Asian, and South East Asian ancestry individuals |
Replication sample | 19,636 East Asian ancestry individuals |
Region | 17q23.2 |
Chromosome id | chr17 |
Chromosome position | 61379228 |
Reported gene | BCAS3 |
Mapped gene | LOC101927855, BCAS3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101927855, 54828 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs9895661-C |
SNPs | rs9895661 |
Merged | 0 |
SNP id current | 9895661 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.52 |
P value | 0.00000000005 |
Pvalue mlog | 10.3010299956639 |
P value text | |
Or beta | 0.0051 |
%95 Ci | [0.0035-0.0067] ml/min/1.73m2 decrease |
Platform | Affymetrix, Illumina [2353587] (imputed) |
CNV | N |
Mapped trait | renal system measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742 |
Study accession | GCST001607 |