SNP Detail For rs9891119
1.Mapping Information
Human SNP ID rs9891119
Human chromosome chr17
Human SNP position 42355962
Pig chromosome chr12
Pig SNP position 20747872
2.Annotation Information
PubMed ID21833088
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21833088
StudyGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Disease/TraitMultiple sclerosis
Initial sample9,772 European ancestry cases, 16,849 European ancestry controls
Replication sample4,218 European ancestry cases, 7,296 European ancestry controls
Region17q21.2
Chromosome idchr17
Chromosome position42355962
Reported geneSTAT3
Mapped geneSTAT3
Upstream gene id
Downstream gene id
SNP gene ids6774
Upstream gene distance
Downstream gene distance
SNP risk allelers9891119-C
SNPsrs9891119
Merged0
SNP id current9891119
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000002
Pvalue mlog9.69897000433601
P value text
Or beta1.11
%95 Ci[1.09-1.12]
PlatformIllumina [465434]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001198
PubMed ID23266558
JournalGastroenterology
Linkwww.ncbi.nlm.nih.gov/pubmed/23266558
StudyA genome-wide association study identifies 2 susceptibility Loci for Crohn__s disease in a Japanese population.
Disease/TraitCrohn__s disease
Initial sample372 Japanese ancestry cases,3,389 Japanese ancestry controls
Replication sampleUp to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls
Region17q21.2
Chromosome idchr17
Chromosome position42355962
Reported geneSTAT3
Mapped geneSTAT3
Upstream gene id
Downstream gene id
SNP gene ids6774
Upstream gene distance
Downstream gene distance
SNP risk allelers9891119-A
SNPsrs9891119
Merged0
SNP id current9891119
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000000000002
Pvalue mlog14.698970004336
P value text
Or beta1.37
%95 Ci[1.27-1.48]
PlatformIllumina [4929034] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST001785