Human SNP ID | rs987237 |
---|---|
Human chromosome | chr6 |
Human SNP position | 50835337 |
Pig chromosome | JH118430-1 |
Pig SNP position | 228091 |
PubMed ID | 19557161 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19557161 |
Study | Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. |
Disease/Trait | Adiposity |
Initial sample | 38,580 European ancestry individuals |
Replication sample | Up to 102,064 European ancestry individuals |
Region | 6p12.3 |
Chromosome id | chr6 |
Chromosome position | 50835337 |
Reported gene | TFAP2B |
Mapped gene | TFAP2B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7021 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs987237-G |
SNPs | rs987237 |
Merged | 0 |
SNP id current | 987237 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.164 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | (WC) |
Or beta | 0.04 |
%95 Ci | [0.03-0.05] z-score unit increase |
Platform | Affymetrix, Illumina [2573738] (imputed) |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST000428 |
PubMed ID | 20935630 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20935630 |
Study | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. |
Disease/Trait | Body mass index |
Initial sample | Up to 123,865 European ancestry individuals |
Replication sample | Up to 125,931 European ancestry individuals |
Region | 6p12.3 |
Chromosome id | chr6 |
Chromosome position | 50835337 |
Reported gene | TFAP2B |
Mapped gene | TFAP2B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7021 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs987237-G |
SNPs | rs987237 |
Merged | 0 |
SNP id current | 987237 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.18 |
P value | 3E-20 |
Pvalue mlog | 19.5228787452803 |
P value text | |
Or beta | 0.13 |
%95 Ci | [0.07-0.19] kg/m2 increase |
Platform | Affymetrix, Illumina, Perlegen [~ 2800000] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST000830 |
PubMed ID | 23563607 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Body mass index |
Initial sample | 7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals |
Replication sample | 4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals |
Region | 6p12.3 |
Chromosome id | chr6 |
Chromosome position | 50835337 |
Reported gene | TFAP2B |
Mapped gene | TFAP2B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7021 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs987237-G |
SNPs | rs987237 |
Merged | 0 |
SNP id current | 987237 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.18 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 1.2 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST001955 |
PubMed ID | 26604143 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26604143 |
Study | Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. |
Disease/Trait | Childhood body mass index |
Initial sample | 34,744 European ancestry children |
Replication sample | 11,313 European ancestry children |
Region | 6p12.3 |
Chromosome id | chr6 |
Chromosome position | 50835337 |
Reported gene | TFAP2B |
Mapped gene | TFAP2B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7021 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs987237-G |
SNPs | rs987237 |
Merged | 0 |
SNP id current | 987237 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.000000000002 |
Pvalue mlog | 11.698970004336 |
P value text | |
Or beta | 0.062 |
%95 Ci | [0.044-0.08] unit increase |
Platform | Affymetrix, Illumina [2499691] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST003177 |