Human SNP ID | rs981844 |
---|---|
Human chromosome | chr4 |
Human SNP position | 153730876 |
Pig chromosome | chr8 |
Pig SNP position | 79792165 |
PubMed ID | 25350695 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25350695 |
Study | Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. |
Disease/Trait | Response to statins (LDL cholesterol change) |
Initial sample | 18,596 European ancestry individuals |
Replication sample | 23,279 European ancestry individuals |
Region | 4q31.3 |
Chromosome id | chr4 |
Chromosome position | 153730876 |
Reported gene | RNF175 |
Mapped gene | LOC105377499, RNF175 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105377499, 285533 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs981844-A |
SNPs | rs981844 |
Merged | 0 |
SNP id current | 981844 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.747 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 0.009 |
%95 Ci | [0.0051-0.0129] unit increase |
Platform | Affymetrix, Illumina, Perlegen [at least 2500000] (imputed) |
CNV | N |
Mapped trait | response to statin, low density lipoprotein cholesterol measurement |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002675 |