Human SNP ID | rs9747992 |
---|---|
Human chromosome | chr17 |
Human SNP position | 79831041 |
Pig chromosome | chr12 |
Pig SNP position | 2599630 |
PubMed ID | 24528284 |
---|---|
Journal | Br J Clin Pharmacol |
Link | www.ncbi.nlm.nih.gov/pubmed/24528284 |
Study | Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations. |
Disease/Trait | Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) |
Initial sample | 300 European ancestry Escitalpram treated individuals, 130 European ancestry Citalopram treated individuals |
Replication sample | NA |
Region | 17q25.3 |
Chromosome id | chr17 |
Chromosome position | 79831041 |
Reported gene | CBX4 |
Mapped gene | LOC105371919 - CBX4 |
Upstream gene id | 105371919 |
Downstream gene id | 8535 |
SNP gene ids | |
Upstream gene distance | 3337 |
Downstream gene distance | 2115 |
SNP risk allele | rs9747992-? |
SNPs | rs9747992 |
Merged | 0 |
SNP id current | 9747992 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.086 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (S-DCT concentration) |
Or beta | |
%95 Ci | |
Platform | Illumina [7537437] (imputed) |
CNV | N |
Mapped trait | unipolar depression, response to selective serotonin reuptake inhibitor |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0005658 |
Study accession | GCST002549 |