SNP Detail For rs972540
1.Mapping Information
Human SNP ID rs972540
Human chromosome chr2
Human SNP position 206380059
Pig chromosome chr15
Pig SNP position 121195199
2.Annotation Information
PubMed ID25673413
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673413
StudyGenetic studies of body mass index yield new insights for obesity biology.
Disease/TraitBody mass index
Initial sampleup to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals
Replication sampleup to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828
Region2q33.3
Chromosome idchr2
Chromosome position206380059
Reported geneADAM23
Mapped geneZDBF2 - HNRNPA1P51
Upstream gene id57683
Downstream gene id729366
SNP gene ids
Upstream gene distance65621
Downstream gene distance38915
SNP risk allelers972540-G
SNPsrs972540
Merged0
SNP id current972540
Contextregulatory_region_variant
Intergenic1
Allele frequency0.269
P value0.0000002
Pvalue mlog6.69897000433601
P value text(EA)
Or beta0.018
%95 Ci[0.011-0.024] kg/m2 increase
PlatformAffymetrix, Illumina [2550021]
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002783
PubMed ID25673413
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673413
StudyGenetic studies of body mass index yield new insights for obesity biology.
Disease/TraitBody mass index
Initial sampleup to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals
Replication sampleup to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828
Region2q33.3
Chromosome idchr2
Chromosome position206380059
Reported geneADAM23
Mapped geneZDBF2 - HNRNPA1P51
Upstream gene id57683
Downstream gene id729366
SNP gene ids
Upstream gene distance65621
Downstream gene distance38915
SNP risk allelers972540-G
SNPsrs972540
Merged0
SNP id current972540
Contextregulatory_region_variant
Intergenic1
Allele frequency0.266
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta0.017
%95 Ci[0.01-0.023] kg/m2 increase
PlatformAffymetrix, Illumina [2550021]
CNVN
Mapped traitbody mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002783