Human SNP ID | rs9525638 |
---|---|
Human chromosome | chr13 |
Human SNP position | 42554441 |
Pig chromosome | chr11 |
Pig SNP position | 25168466 |
PubMed ID | 22792071 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22792071 |
Study | WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. |
Disease/Trait | Cortical thickness |
Initial sample | 5,878 European ancestry individuals |
Replication sample | 1,032 European ancestry individuals |
Region | 13q14.11 |
Chromosome id | chr13 |
Chromosome position | 42554441 |
Reported gene | TNFSF11, RANKL |
Mapped gene | LOC105370177 - TNFSF11 |
Upstream gene id | 105370177 |
Downstream gene id | 8600 |
SNP gene ids | |
Upstream gene distance | 68485 |
Downstream gene distance | 8295 |
SNP risk allele | rs9525638-T |
SNPs | rs9525638 |
Merged | 0 |
SNP id current | 9525638 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000000004 |
Pvalue mlog | 8.39794000867203 |
P value text | |
Or beta | 0.09 |
%95 Ci | [0.051-0.129] mm decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cortical thickness |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004840 |
Study accession | GCST001593 |
PubMed ID | 24945404 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24945404 |
Study | Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. |
Disease/Trait | Bone mineral density (paediatric, upper limb) |
Initial sample | 8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children |
Replication sample | NA |
Region | 13q14.11 |
Chromosome id | chr13 |
Chromosome position | 42554441 |
Reported gene | TNFSF11 |
Mapped gene | LOC105370177 - TNFSF11 |
Upstream gene id | 105370177 |
Downstream gene id | 8600 |
SNP gene ids | |
Upstream gene distance | 68485 |
Downstream gene distance | 8295 |
SNP risk allele | rs9525638-C |
SNPs | rs9525638 |
Merged | 0 |
SNP id current | 9525638 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.42 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | |
Or beta | 0.089 |
%95 Ci | [0.060-0.118] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST002496 |
PubMed ID | 24945404 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24945404 |
Study | Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. |
Disease/Trait | Bone mineral density (paediatric, upper limb) |
Initial sample | 8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children |
Replication sample | NA |
Region | 13q14.11 |
Chromosome id | chr13 |
Chromosome position | 42554441 |
Reported gene | TNFSF11 |
Mapped gene | LOC105370177 - TNFSF11 |
Upstream gene id | 105370177 |
Downstream gene id | 8600 |
SNP gene ids | |
Upstream gene distance | 68485 |
Downstream gene distance | 8295 |
SNP risk allele | rs9525638-C |
SNPs | rs9525638 |
Merged | 0 |
SNP id current | 9525638 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | (EA) |
Or beta | 0.0949 |
%95 Ci | [0.062-0.128] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST002496 |