Human SNP ID | rs9466056 |
---|---|
Human chromosome | chr6 |
Human SNP position | 21384382 |
Pig chromosome | chr7 |
Pig SNP position | 17611110 |
PubMed ID | 21533022 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21533022 |
Study | Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. |
Disease/Trait | Bone mineral density |
Initial sample | 900 European ancestry female individuals with low hip bone mineral density, 1,055 European ancestry female individuals with high hip bone mineral density |
Replication sample | 20,898 European ancestry female individuals |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 21384382 |
Reported gene | SOX4 |
Mapped gene | CDKAL1 - LINC00581 |
Upstream gene id | 54901 |
Downstream gene id | 100874531 |
SNP gene ids | |
Upstream gene distance | 151978 |
Downstream gene distance | 101679 |
SNP risk allele | rs9466056-G |
SNPs | rs9466056 |
Merged | 0 |
SNP id current | 9466056 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (femoral neck) |
Or beta | 0.05 |
%95 Ci | [NR] unit increase |
Platform | Illumina [2543887] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST001050 |
PubMed ID | 22504420 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22504420 |
Study | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. |
Disease/Trait | Bone mineral density |
Initial sample | Up to 32,961 European and East Asian ancestry individuals |
Replication sample | Up to 50,933 European and East Asian ancestry individuals |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 21384382 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 - LINC00581 |
Upstream gene id | 54901 |
Downstream gene id | 100874531 |
SNP gene ids | |
Upstream gene distance | 151978 |
Downstream gene distance | 101679 |
SNP risk allele | rs9466056-A |
SNPs | rs9466056 |
Merged | 0 |
SNP id current | 9466056 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.38 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | (FNBMD) |
Or beta | 0.04 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST001482 |