Human SNP ID | rs9420790 |
---|---|
Human chromosome | chr10 |
Human SNP position | 100496440 |
Pig chromosome | chr4 |
Pig SNP position | 63941925 |
PubMed ID | 23400010 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/23400010 |
Study | Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. |
Disease/Trait | Thiazide-induced adverse metabolic effects in hypertensive patients |
Initial sample | 425 European ancestry cases, 342 African American cases |
Replication sample | NA |
Region | 10q24.31 |
Chromosome id | chr10 |
Chromosome position | 100496440 |
Reported gene | ERLIN1 |
Mapped gene | SEC31B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 25956 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs9420790-A |
SNPs | rs9420790 |
Merged | 0 |
SNP id current | 9420790 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.08 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (AA-triglyceride response) |
Or beta | 34.63 |
%95 Ci | [20.46-48.8] mg/dL decrease |
Platform | Affymetrix, Illumina [> 2000000] (imputed) |
CNV | N |
Mapped trait | response to hydrochlorothiazide, triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST001859 |