SNP Detail For rs9420790
1.Mapping Information
Human SNP ID rs9420790
Human chromosome chr10
Human SNP position 100496440
Pig chromosome chr4
Pig SNP position 63941925
2.Annotation Information
PubMed ID23400010
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/23400010
StudyGenome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
Disease/TraitThiazide-induced adverse metabolic effects in hypertensive patients
Initial sample425 European ancestry cases, 342 African American cases
Replication sampleNA
Region10q24.31
Chromosome idchr10
Chromosome position100496440
Reported geneERLIN1
Mapped geneSEC31B
Upstream gene id
Downstream gene id
SNP gene ids25956
Upstream gene distance
Downstream gene distance
SNP risk allelers9420790-A
SNPsrs9420790
Merged0
SNP id current9420790
Contextintron_variant
Intergenic0
Allele frequency0.08
P value0.000002
Pvalue mlog5.69897000433601
P value text(AA-triglyceride response)
Or beta34.63
%95 Ci[20.46-48.8] mg/dL decrease
PlatformAffymetrix, Illumina [> 2000000] (imputed)
CNVN
Mapped traitresponse to hydrochlorothiazide, triglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST001859