SNP Detail For rs9402686
1.Mapping Information
Human SNP ID rs9402686
Human chromosome chr6
Human SNP position 135106679
Pig chromosome chr1
Pig SNP position 32412680
2.Annotation Information
PubMed ID19820697
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19820697
StudyA genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
Disease/TraitHematological parameters
Initial sample4,627 European ancestry individuals
Replication sample9,316 European ancestry individuals
Region6q23.3
Chromosome idchr6
Chromosome position135106679
Reported geneHBS1L, MYB
Mapped geneHBS1L - LOC105378010
Upstream gene id10767
Downstream gene id105378010
SNP gene ids
Upstream gene distance51781
Downstream gene distance166
SNP risk allelers9402686-A
SNPsrs9402686
Merged0
SNP id current9402686
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value7E-42
Pvalue mlog41.1549019599857
P value text(MCV)
Or beta0.82
%95 Ci[0.70-0.94] fl increase
PlatformAffymetrix, Illumina [~ 2110000] (imputed)
CNVN
Mapped traitmean corpuscular volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004526
Study accessionGCST000498
PubMed ID25096241
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25096241
StudyTrans-ethnic meta-analysis of white blood cell phenotypes.
Disease/TraitWhite blood cell count
Initial sample16,843 Japanese ancestry individuals, 19,509 European ancestry individuals, 16,388 African American individuals
Replication sampleNA
Region6q23.3
Chromosome idchr6
Chromosome position135106679
Reported geneNR
Mapped geneHBS1L - LOC105378010
Upstream gene id10767
Downstream gene id105378010
SNP gene ids
Upstream gene distance51781
Downstream gene distance166
SNP risk allelers9402686-?
SNPsrs9402686
Merged0
SNP id current9402686
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000000000004
Pvalue mlog11.397940008672
P value text
Or beta0.0138
%95 Ci[0.0099-0.0177] unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitleukocyte count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004308
Study accessionGCST002556