SNP Detail For rs9358749
1.Mapping Information
Human SNP ID rs9358749
Human chromosome chr6
Human SNP position 24077829
Pig chromosome chr7
Pig SNP position 20110884
2.Annotation Information
PubMed ID25461247
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25461247
StudyGenome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.
Disease/TraitResponse to abacavir-containing treatment in HIV-1 infection (virologic failure)
Initial sampleUp 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals
Replication sampleNA
Region6p22.3
Chromosome idchr6
Chromosome position24077829
Reported geneNR
Mapped geneLOC100128365 - NRSN1
Upstream gene id100128365
Downstream gene id140767
SNP gene ids
Upstream gene distance104478
Downstream gene distance48357
SNP risk allelers9358749-T
SNPsrs9358749
Merged0
SNP id current9358749
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.000005
Pvalue mlog5.30102999566398
P value text(phenotype 3)
Or beta3.27
%95 Ci[NR]
PlatformIllumina [> 8000000] (imputed)
CNVN
Mapped traitHIV-1 infection, virologic response measurement, response to abacavir
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905
Study accessionGCST002769
PubMed ID25461247
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25461247
StudyGenome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols.
Disease/TraitResponse to efavirenz-containing treatment in HIV 1 infection (virologic failure)
Initial sampleUp to 737 European ancestry individuals, Up to 545 Black individuals, Up to 314 Hispanic individuals
Replication sampleNA
Region6p22.3
Chromosome idchr6
Chromosome position24077829
Reported geneNR
Mapped geneLOC100128365 - NRSN1
Upstream gene id100128365
Downstream gene id140767
SNP gene ids
Upstream gene distance104478
Downstream gene distance48357
SNP risk allelers9358749-T
SNPsrs9358749
Merged0
SNP id current9358749
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.000005
Pvalue mlog5.30102999566398
P value text(phenotype 1)
Or beta3.27
%95 Ci[NR]
PlatformIllumina [> 8000000] (imputed)
CNVN
Mapped traitHIV-1 infection, response to efavirenz, virologic response measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0006906
Study accessionGCST002771