SNP Detail For rs9298506
1.Mapping Information
Human SNP ID rs9298506
Human chromosome chr8
Human SNP position 54524964
Pig chromosome chr4
Pig SNP position 83860713
2.Annotation Information
PubMed ID18997786
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18997786
StudySusceptibility loci for intracranial aneurysm in European and Japanese populations.
Disease/TraitIntracranial aneurysm
Initial sample1,580 European ancestry cases, 6,276 European ancestry controls
Replication sample495 Japanese ancestry cases, 676 Japanese ancestry controls
Region8q11.23
Chromosome idchr8
Chromosome position54524964
Reported geneSOX17
Mapped geneSEC11B - RP1
Upstream gene id157708
Downstream gene id6101
SNP gene ids
Upstream gene distance1583
Downstream gene distance91103
SNP risk allelers9298506-A
SNPsrs9298506
Merged0
SNP id current9298506
Contextupstream_gene_variant
Intergenic1
Allele frequency0.81
P value0.000000002
Pvalue mlog8.69897000433601
P value text
Or beta1.35
%95 Ci[1.22-1.49]
PlatformIllumina [289271]
CNVN
Mapped traitbrain aneurysm
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003870
Study accessionGCST000262
PubMed ID20364137
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20364137
StudyGenome-wide association study of intracranial aneurysm identifies three new risk loci.
Disease/TraitIntracranial aneurysm
Initial sample2,780 European ancestry cases, 12,515 European ancestry controls
Replication sample3,111 Japanese ancestry cases, 1,666 Japanese ancestry controls
Region8q11.23
Chromosome idchr8
Chromosome position54524964
Reported geneSOX17
Mapped geneSEC11B - RP1
Upstream gene id157708
Downstream gene id6101
SNP gene ids
Upstream gene distance1583
Downstream gene distance91103
SNP risk allelers9298506-A
SNPsrs9298506
Merged0
SNP id current9298506
Contextupstream_gene_variant
Intergenic1
Allele frequency0.81
P value0.000000000001
Pvalue mlog12
P value text
Or beta1.28
%95 Ci[1.20-1.38]
PlatformIllumina [831534] (imputed)
CNVN
Mapped traitbrain aneurysm
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003870
Study accessionGCST000646