Human SNP ID | rs9292777 |
---|---|
Human chromosome | chr5 |
Human SNP position | 40437846 |
Pig chromosome | chr16 |
Pig SNP position | 26741937 |
PubMed ID | 17554261 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/17554261 |
Study | Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn__s disease susceptibility. |
Disease/Trait | Crohn__s disease |
Initial sample | 1,748 cases, 2,938 controls |
Replication sample | 1,182 European ancestry cases, 2,024 European ancestry controls |
Region | 5p13.1 |
Chromosome id | chr5 |
Chromosome position | 40437846 |
Reported gene | intergenic |
Mapped gene | LOC105374736 - LOC105374737 |
Upstream gene id | 105374736 |
Downstream gene id | 105374737 |
SNP gene ids | |
Upstream gene distance | 91291 |
Downstream gene distance | 162034 |
SNP risk allele | rs9292777-? |
SNPs | rs9292777 |
Merged | 0 |
SNP id current | 9292777 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.4 |
P value | 0.000000000000000003 |
Pvalue mlog | 17.5228787452803 |
P value text | |
Or beta | 1.34 |
%95 Ci | [1.20-1.50] |
Platform | Affymetrix [see WTCCC] |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST000039 |
PubMed ID | 22570697 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/22570697 |
Study | Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1. |
Disease/Trait | Multiple sclerosis |
Initial sample | 2,127 European ancestry cases, 4,558 European ancestry controls |
Replication sample | 2,785 European ancestry cases, 2,940 European ancestry controls |
Region | 5p13.1 |
Chromosome id | chr5 |
Chromosome position | 40437846 |
Reported gene | PTGER4 |
Mapped gene | LOC105374736 - LOC105374737 |
Upstream gene id | 105374736 |
Downstream gene id | 105374737 |
SNP gene ids | |
Upstream gene distance | 91291 |
Downstream gene distance | 162034 |
SNP risk allele | rs9292777-T |
SNPs | rs9292777 |
Merged | 0 |
SNP id current | 9292777 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.19 |
%95 Ci | [1.12-1.25] |
Platform | Affymetrix, Illumina [130903] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST001505 |
PubMed ID | 22412388 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22412388 |
Study | A genome-wide scan of Ashkenazi Jewish Crohn__s disease suggests novel susceptibility loci. |
Disease/Trait | Crohn__s disease |
Initial sample | 737 Ashkenazi Jewish cases, 2,257 Ashkenazi Jewish controls |
Replication sample | 971 Ashkenazi Jewish cases, 2,124 Ashkenazi Jewish controls |
Region | 5p13.1 |
Chromosome id | chr5 |
Chromosome position | 40437846 |
Reported gene | PTGER4 |
Mapped gene | LOC105374736 - LOC105374737 |
Upstream gene id | 105374736 |
Downstream gene id | 105374737 |
SNP gene ids | |
Upstream gene distance | 91291 |
Downstream gene distance | 162034 |
SNP risk allele | rs9292777-T |
SNPs | rs9292777 |
Merged | 0 |
SNP id current | 9292777 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.597 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 1.37 |
%95 Ci | [1.28-1.48] |
Platform | Affymetrix, Illumina [1060934] (imputed) |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST001438 |