Human SNP ID | rs9275572 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32711222 |
Pig chromosome | chr7 |
Pig SNP position | 29228737 |
PubMed ID | 20596022 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20596022 |
Study | Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. |
Disease/Trait | Alopecia areata |
Initial sample | Up to 1,054 European ancestry cases, 3,278 European ancestry controls |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32711222 |
Reported gene | HLA-DQA2 |
Mapped gene | HLA-DQB1 - LOC102725019 |
Upstream gene id | 3119 |
Downstream gene id | 102725019 |
SNP gene ids | |
Upstream gene distance | 44533 |
Downstream gene distance | 6794 |
SNP risk allele | rs9275572-G |
SNPs | rs9275572 |
Merged | 0 |
SNP id current | 9275572 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.59 |
P value | 1E-35 |
Pvalue mlog | 35 |
P value text | |
Or beta | 2.21 |
%95 Ci | [1.98-2.47] |
Platform | Illumina [463301] |
CNV | N |
Mapped trait | alopecia areata |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004192 |
Study accession | GCST000719 |
PubMed ID | 21499248 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21499248 |
Study | Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. |
Disease/Trait | Hepatocellular carcinoma |
Initial sample | 721 Japanese ancestry cases, 2,890 Japanese ancestry controls |
Replication sample | 673 Japanese ancestry cases, 2,596 Japanese ancestry controls |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32711222 |
Reported gene | HLA-DQ, HLA-DR |
Mapped gene | HLA-DQB1 - LOC102725019 |
Upstream gene id | 3119 |
Downstream gene id | 102725019 |
SNP gene ids | |
Upstream gene distance | 44533 |
Downstream gene distance | 6794 |
SNP risk allele | rs9275572-A |
SNPs | rs9275572 |
Merged | 0 |
SNP id current | 9275572 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.36 |
P value | 0.000000006 |
Pvalue mlog | 8.22184874961635 |
P value text | |
Or beta | 1.3 |
%95 Ci | [1.19-1.42] |
Platform | Illumina [432703] |
CNV | N |
Mapped trait | hepatocellular carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000182 |
Study accession | GCST001041 |
PubMed ID | 24871463 |
Journal | Genes Immun |
Link | www.ncbi.nlm.nih.gov/pubmed/24871463 |
Study | GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 725 European ancestry cases, 2,438 European ancestry controls |
Replication sample | NA |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32711222 |
Reported gene | HLA-DQA2 |
Mapped gene | HLA-DQB1 - LOC102725019 |
Upstream gene id | 3119 |
Downstream gene id | 102725019 |
SNP gene ids | |
Upstream gene distance | 44533 |
Downstream gene distance | 6794 |
SNP risk allele | rs9275572-A |
SNPs | rs9275572 |
Merged | 0 |
SNP id current | 9275572 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.4 |
P value | 0.0000000000000005 |
Pvalue mlog | 15.3010299956639 |
P value text | |
Or beta | 1.74 |
%95 Ci | [1.64-1.85] |
Platform | Illumina [NR] |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST002463 |
PubMed ID | 24376798 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/24376798 |
Study | HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study. |
Disease/Trait | Chronic hepatitis C infection |
Initial sample | 481 Japanese ancestry cases, 2,963 Japanese ancestry controls |
Replication sample | 5,737 Japanese ancestry cases, 26,931 Japanese ancestry controls |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32711222 |
Reported gene | HLA-DQB1, HLA-DQA1 |
Mapped gene | HLA-DQB1 - LOC102725019 |
Upstream gene id | 3119 |
Downstream gene id | 102725019 |
SNP gene ids | |
Upstream gene distance | 44533 |
Downstream gene distance | 6794 |
SNP risk allele | rs9275572-T |
SNPs | rs9275572 |
Merged | 0 |
SNP id current | 9275572 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.359 |
P value | 0.0000000000000004 |
Pvalue mlog | 15.397940008672 |
P value text | |
Or beta | 1.27 |
%95 Ci | [1.19-1.33] |
Platform | Illumina [458207] |
CNV | N |
Mapped trait | Chronic Hepatitis C infection |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004220 |
Study accession | GCST002316 |