SNP Detail For rs9271858
1.Mapping Information
Human SNP ID rs9271858
Human chromosome chr6
Human SNP position 32627446
Pig chromosome chr7
Pig SNP position 29347367
2.Annotation Information
PubMed ID23291585
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23291585
StudyCommon variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.
Disease/TraitLeishmaniasis (visceral)
Initial sample989 Indian ancestry cases, 1,089 Indian ancestry controls, 357 Brazilian ancestry cases, 1,613 Brazilian ancestry unaffected relatives
Replication sample951 Indian ancestry cases, 990 Indian ancestry controls
Region6p21.32
Chromosome idchr6
Chromosome position32627446
Reported geneHLA, HLA-DRB1, HLA-DQA1
Mapped geneHLA-DRB1 - HLA-DQA1
Upstream gene id3123
Downstream gene id3117
SNP gene ids
Upstream gene distance37610
Downstream gene distance9950
SNP risk allelers9271858-G
SNPsrs9271858
Merged0
SNP id current9271858
Contextupstream_gene_variant
Intergenic1
Allele frequency0.39
P value0.00000000000000003
Pvalue mlog16.5228787452803
P value text
Or beta1.41
%95 Ci[1.30-1.52]
PlatformIllumina [521134]
CNVN
Mapped traitvisceral Leishmaniasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005045
Study accessionGCST001805