Human SNP ID | rs9271858 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32627446 |
Pig chromosome | chr7 |
Pig SNP position | 29347367 |
PubMed ID | 23291585 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23291585 |
Study | Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. |
Disease/Trait | Leishmaniasis (visceral) |
Initial sample | 989 Indian ancestry cases, 1,089 Indian ancestry controls, 357 Brazilian ancestry cases, 1,613 Brazilian ancestry unaffected relatives |
Replication sample | 951 Indian ancestry cases, 990 Indian ancestry controls |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32627446 |
Reported gene | HLA, HLA-DRB1, HLA-DQA1 |
Mapped gene | HLA-DRB1 - HLA-DQA1 |
Upstream gene id | 3123 |
Downstream gene id | 3117 |
SNP gene ids | |
Upstream gene distance | 37610 |
Downstream gene distance | 9950 |
SNP risk allele | rs9271858-G |
SNPs | rs9271858 |
Merged | 0 |
SNP id current | 9271858 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.39 |
P value | 0.00000000000000003 |
Pvalue mlog | 16.5228787452803 |
P value text | |
Or beta | 1.41 |
%95 Ci | [1.30-1.52] |
Platform | Illumina [521134] |
CNV | N |
Mapped trait | visceral Leishmaniasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005045 |
Study accession | GCST001805 |