SNP Detail For rs9262631
1.Mapping Information
Human SNP ID rs9262631
Human chromosome chr6
Human SNP position 31056824
Pig chromosome chr7
Pig SNP position 27349773
2.Annotation Information
PubMed ID26151496
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/26151496
StudyGenetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.
Disease/TraitThionamide-induced agranulocytosis in Graves__ disease
Initial sample21 East Asian ancestry cases with agranulocytosis, 662 East Asian ancestry cases without agranulocytosis
Replication sample21 East Asian ancestry cases with agranulocytosis, 546 East Asian ancestry cases without agranulocytosis
Region6p21.33
Chromosome idchr6
Chromosome position31056824
Reported geneHLA
Mapped geneHCG22
Upstream gene id
Downstream gene id
SNP gene ids285834
Upstream gene distance
Downstream gene distance
SNP risk allelers9262631-A
SNPsrs9262631
Merged
SNP id current9262631
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.063
P value6E-19
Pvalue mlog18.2218487496163
P value text(trend)
Or beta7.09
%95 Ci[4.32-11.63] (allelic)
PlatformAffymetrix [522980]
CNVN
Mapped traitdrug-induced agranulocytosis, response to thioamide, Graves disease
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://www.ebi.ac.uk/efo/EFO_0007633, http://www.ebi.ac.uk/efo/EFO_0004237
Study accessionGCST003018