Human SNP ID | rs925489 |
---|---|
Human chromosome | chr9 |
Human SNP position | 97784318 |
Pig chromosome | chr1 |
Pig SNP position | 267770738 |
PubMed ID | 22493691 |
---|---|
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/22493691 |
Study | Novel associations for hypothyroidism include known autoimmune risk loci. |
Disease/Trait | Hypothyroidism |
Initial sample | 3,736 European ancestry cases, 35,546 European ancestry controls |
Replication sample | NA |
Region | 9q22.33 |
Chromosome id | chr9 |
Chromosome position | 97784318 |
Reported gene | KRT18P13, FOXE1, C9orf156 |
Mapped gene | PTCSC2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101928337 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs925489-T |
SNPs | rs925489 |
Merged | 0 |
SNP id current | 925489 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.668 |
P value | 2E-19 |
Pvalue mlog | 18.698970004336 |
P value text | |
Or beta | 1.28 |
%95 Ci | [1.22-1.35] |
Platform | Illumina [870065] |
CNV | N |
Mapped trait | hypothyroidism |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004705 |
Study accession | GCST001474 |
PubMed ID | 24852370 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24852370 |
Study | Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations. |
Disease/Trait | Serum thyroid-stimulating hormone levels |
Initial sample | 1,346 Han Chinese ancestry individuals |
Replication sample | 3,235 She Chinese ancestry individuals |
Region | 9q22.33 |
Chromosome id | chr9 |
Chromosome position | 97784318 |
Reported gene | XPA, FOXE1 |
Mapped gene | PTCSC2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 101928337 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs925489-C |
SNPs | rs925489 |
Merged | 0 |
SNP id current | 925489 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.109 |
P value | 0.0000000000001 |
Pvalue mlog | 13 |
P value text | |
Or beta | 0.058 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [8503852] (imputed) |
CNV | N |
Mapped trait | thyroid stimulating hormone measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004748 |
Study accession | GCST002458 |