SNP Detail For rs915650
1.Mapping Information
Human SNP ID rs915650
Human chromosome chr8
Human SNP position 37800008
Pig chromosome chr15
Pig SNP position 55724630
2.Annotation Information
PubMed ID26121980
JournalBMC Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/26121980
StudyGenome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.
Disease/TraitTriptolide cytotoxicity
Initial sample55 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region8p11.23
Chromosome idchr8
Chromosome position37800008
Reported geneintergenic
Mapped geneADGRA2
Upstream gene id
Downstream gene id
SNP gene ids25960
Upstream gene distance
Downstream gene distance
SNP risk allelers915650-?
SNPsrs915650
Merged
SNP id current915650
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000003
Pvalue mlog5.52287874528033
P value text
Or beta0.59
%95 Ciunit decrease
PlatformNR [at least 1978803] (imputed)
CNVN
Mapped traitresponse to triptolide, cytotoxicity measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007662, http://www.ebi.ac.uk/efo/EFO_0006952
Study accessionGCST003008