SNP Detail For rs905739
1.Mapping Information
Human SNP ID rs905739
Human chromosome chr15
Human SNP position 78552768
Pig chromosome chr7
Pig SNP position 52926799
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78552768
Reported geneIntergenic
Mapped genePSMA4 - CHRNA5
Upstream gene id5685
Downstream gene id1138
SNP gene ids
Upstream gene distance3548
Downstream gene distance12752
SNP risk allelers905739-A
SNPsrs905739
Merged0
SNP id current905739
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.781
P value0.00000000007
Pvalue mlog10.1549019599857
P value text
Or beta0.069
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78552768
Reported geneIntergenic
Mapped genePSMA4 - CHRNA5
Upstream gene id5685
Downstream gene id1138
SNP gene ids
Upstream gene distance3548
Downstream gene distance12752
SNP risk allelers905739-A
SNPsrs905739
Merged0
SNP id current905739
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.781
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.012
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264