SNP Detail For rs900
1.Mapping Information
Human SNP ID rs900
Human chromosome chr1
Human SNP position 218441563
Pig chromosome chr10
Pig SNP position 10474465
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218441563
Reported geneTGFB2
Mapped geneTGFB2
Upstream gene id
Downstream gene id
SNP gene ids7042
Upstream gene distance
Downstream gene distance
SNP risk allelers900-A
SNPsrs900
Merged0
SNP id current900
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.714
P value0.000001
Pvalue mlog6
P value text
Or beta0.046
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218441563
Reported geneTGFB2
Mapped geneTGFB2
Upstream gene id
Downstream gene id
SNP gene ids7042
Upstream gene distance
Downstream gene distance
SNP risk allelers900-A
SNPsrs900
Merged0
SNP id current900
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.713
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.011
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264