SNP Detail For rs892085
1.Mapping Information
Human SNP ID rs892085
Human chromosome chr19
Human SNP position 10707416
Pig chromosome chr2
Pig SNP position 69851254
2.Annotation Information
PubMed ID25574825
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25574825
StudyGenome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms.
Disease/TraitPsoriasis
Initial sample4,212 European ancestry cases, 8,032 European ancestry controls
Replication sampleNA
Region19p13.2
Chromosome idchr19
Chromosome position10707416
Reported geneILF3, CARM1
Mapped geneQTRT1
Upstream gene id
Downstream gene id
SNP gene ids81890
Upstream gene distance
Downstream gene distance
SNP risk allelers892085-A
SNPsrs892085
Merged0
SNP id current892085
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.172
%95 Ci[1.103-1.245]
PlatformAffymetrix, Illumina, Perlegen [up to 5493100] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002738
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region19p13.2
Chromosome idchr19
Chromosome position10707416
Reported geneILF3, QTRT1
Mapped geneQTRT1
Upstream gene id
Downstream gene id
SNP gene ids81890
Upstream gene distance
Downstream gene distance
SNP risk allelers892085-A
SNPsrs892085
Merged0
SNP id current892085
Contextintron_variant
Intergenic0
Allele frequency0.566
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.16
%95 Ci[1.09-1.23]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874
PubMed ID26626624
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26626624
StudyGenome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
Disease/TraitPsoriasis vulgaris
Initial sample4,007 European ancestry cases, 4,934 European ancestry controls
Replication sampleup to 9,075 European ancestry cases, up to European ancestry 12,726 controls
Region19p13.2
Chromosome idchr19
Chromosome position10707416
Reported geneILF3, CARM1
Mapped geneQTRT1
Upstream gene id
Downstream gene id
SNP gene ids81890
Upstream gene distance
Downstream gene distance
SNP risk allelers892085-A
SNPsrs892085
Merged0
SNP id current892085
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000008
Pvalue mlog6.09691001300805
P value text
Or beta1.114
%95 CiNR
PlatformIllumina [up to 11532644] (imputed)
CNVN
Mapped trait
Mapped trait URI
Study accessionGCST003268