Human SNP ID | rs880315 |
---|---|
Human chromosome | chr1 |
Human SNP position | 10736809 |
Pig chromosome | chr6 |
Pig SNP position | 64897724 |
PubMed ID | 21572416 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21572416 |
Study | Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. |
Disease/Trait | Blood pressure |
Initial sample | 19,608 East Asian ancestry individuals |
Replication sample | 30,765 East Asian ancestry individuals |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-C |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.65 |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | (Systolic) |
Or beta | 0.74 |
%95 Ci | [0.45-1.03] mm Hg increase |
Platform | Affymetrix, Illumina [1700000] (imputed) |
CNV | N |
Mapped trait | systolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006335 |
Study accession | GCST001072 |
PubMed ID | 21572416 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21572416 |
Study | Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. |
Disease/Trait | Blood pressure |
Initial sample | 19,608 East Asian ancestry individuals |
Replication sample | 30,765 East Asian ancestry individuals |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-C |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.65 |
P value | 0.0000000003 |
Pvalue mlog | 9.52287874528033 |
P value text | (Diastolic) |
Or beta | 0.56 |
%95 Ci | [0.38-0.74] mm Hg increase |
Platform | Affymetrix, Illumina [1700000] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST001074 |
PubMed ID | 25249183 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25249183 |
Study | Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. |
Disease/Trait | Systolic blood pressure |
Initial sample | 11,816 Han Chinese ancestry individuals |
Replication sample | 69,146 Han Chinese ancestry individuals |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-C |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 0.0000000006 |
Pvalue mlog | 9.22184874961635 |
P value text | |
Or beta | 0.97 |
%95 Ci | [0.66-1.28] unit increase |
Platform | Affymetrix, Illumina [2485448] (imputed) |
CNV | N |
Mapped trait | systolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006335 |
Study accession | GCST002630 |
PubMed ID | 25249183 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25249183 |
Study | Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. |
Disease/Trait | Diastolic blood pressure |
Initial sample | 11,816 Han Chinese ancestry individuals |
Replication sample | 69,146 Han Chinese ancestry individuals |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-C |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 0.00000008 |
Pvalue mlog | 7.09691001300805 |
P value text | |
Or beta | 0.46 |
%95 Ci | [0.28-0.64] unit increase |
Platform | Affymetrix, Illumina [2485448] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST002631 |
PubMed ID | 25249183 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25249183 |
Study | Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. |
Disease/Trait | Hypertension |
Initial sample | 5,065 Han Chinese ancestry cases, 4,404 Han Chinese ancestry controls |
Replication sample | 29,799 Han Chinese ancestry cases, 39,347 Han Chinese ancestry controls |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-C |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [2485448] (imputed) |
CNV | N |
Mapped trait | hypertension |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000537 |
Study accession | GCST002627 |
PubMed ID | 26631737 |
Journal | Diabetes |
Link | www.ncbi.nlm.nih.gov/pubmed/26631737 |
Study | Genome-wide Association Studies Identify Genetic Loci Associated with Albuminuria in Diabetes. |
Disease/Trait | Urinary albumin-to-creatinine ratio |
Initial sample | up to 54,450 European ancestry individuals |
Replication sample | NA |
Region | 1p36.22 |
Chromosome id | chr1 |
Chromosome position | 10736809 |
Reported gene | CASZ1 |
Mapped gene | CASZ1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54897 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs880315-T |
SNPs | rs880315 |
Merged | 0 |
SNP id current | 880315 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.65 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | |
Or beta | 0.042 |
%95 Ci | [0.024-0.06] unit decrease |
Platform | Affymetrix, Illumina [2191945] (imputed) |
CNV | N |
Mapped trait | |
Mapped trait URI | |
Study accession | GCST003255 |