SNP Detail For rs868153
1.Mapping Information
Human SNP ID rs868153
Human chromosome chr6
Human SNP position 122068809
Pig chromosome chr1
Pig SNP position 44983852
2.Annotation Information
PubMed ID25241763
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25241763
StudyMeta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.
Disease/TraitVertical cup-disc ratio
Initial sample18,963 European ancestry individuals, 2,131 Erasmus Rucphen individuals
Replication sample2,453 Chinese ancestry individuals, 2,026 Indian ancestry individuals, 2,305 Malay ancestry individuals
Region6q22.31
Chromosome idchr6
Chromosome position122068809
Reported geneHSF2
Mapped geneLOC105377979 - HSF2
Upstream gene id105377979
Downstream gene id3298
SNP gene ids
Upstream gene distance13159
Downstream gene distance330742
SNP risk allelers868153-G
SNPsrs868153
Merged0
SNP id current868153
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.00000001
Pvalue mlog8
P value text
Or beta0.007
%95 Ci[0.0050-0.0090] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitoptic disc size measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004832
Study accessionGCST002626