Human SNP ID | rs852069 |
---|---|
Human chromosome | chr20 |
Human SNP position | 17141948 |
Pig chromosome | chr17 |
Pig SNP position | 28922581 |
PubMed ID | 21102462 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21102462 |
Study | Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. |
Disease/Trait | Menarche (age at onset) |
Initial sample | 86,142 European ancestry female individuals, 557 Old Order Amish female individuals, 1,103 Erasmus Rucphen female individuals |
Replication sample | Up to 12,813 European ancestry female individuals, 910 Val Borbera female individuals, 348 Orcadian female individuals, 338 Friuli Venezia Giulia female individuals, 322 Carlantino female individuals |
Region | 20p12.1 |
Chromosome id | chr20 |
Chromosome position | 17141948 |
Reported gene | PCSK2 |
Mapped gene | LOC105372544 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372544 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs852069-A |
SNPs | rs852069 |
Merged | 0 |
SNP id current | 852069 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.37 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 2.1 |
%95 Ci | [1.32-2.88] week decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST000880 |
PubMed ID | 25231870 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25231870 |
Study | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. |
Disease/Trait | Menarche (age at onset) |
Initial sample | Up to 182,413 European ancestry females |
Replication sample | NA |
Region | 20p12.1 |
Chromosome id | chr20 |
Chromosome position | 17141948 |
Reported gene | PCSK2 |
Mapped gene | LOC105372544 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105372544 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs852069-G |
SNPs | rs852069 |
Merged | 0 |
SNP id current | 852069 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.64 |
P value | 0.0000000000001 |
Pvalue mlog | 13 |
P value text | |
Or beta | 0.04 |
%95 Ci | [0.03-0.05] unit increase |
Platform | Affymetrix, Illumina [2441815] (imputed) |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST002541 |