SNP Detail For rs837841
1.Mapping Information
Human SNP ID rs837841
Human chromosome chr2
Human SNP position 129276439
Pig chromosome chr15
Pig SNP position 64390210
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)
Initial sample147 Japanese ancestry cases, 233 Japanese ancestry controls
Replication sampleNA
Region2q21.1
Chromosome idchr2
Chromosome position129276439
Reported geneLOC151121
Mapped geneLOC105373612
Upstream gene id
Downstream gene id
SNP gene ids105373612
Upstream gene distance
Downstream gene distance
SNP risk allelers837841-T
SNPsrs837841
Merged0
SNP id current837841
Contextupstream_gene_variant
Intergenic0
Allele frequency0.662
P value0.000008
Pvalue mlog5.09691001300805
P value text(Recessive model)
Or beta1.279
%95 Ci[0.930-1.759]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to docetaxel, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1902519, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST001995