SNP Detail For rs8321
1.Mapping Information
Human SNP ID rs8321
Human chromosome chr6
Human SNP position 30064745
Pig chromosome chr7
Pig SNP position 24996841
2.Annotation Information
PubMed ID19115949
JournalJ Infect Dis
Linkwww.ncbi.nlm.nih.gov/pubmed/19115949
StudyGenomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).
Disease/TraitAIDS progression
Initial sample275 European ancestry seropositive non-progressors, 86 European ancestry seropositive rapid progressors, 1,352 European ancestry seronegative controls
Replication sample(see Fellay 2007)
Region6p22.1
Chromosome idchr6
Chromosome position30064745
Reported geneZNRD1, RNF39
Mapped geneZNRD1
Upstream gene id
Downstream gene id
SNP gene ids30834
Upstream gene distance
Downstream gene distance
SNP risk allelers8321-G
SNPsrs8321
Merged0
SNP id current8321
Context3_prime_UTR_variant
Intergenic0
Allele frequencyNR
P value0.0000005
Pvalue mlog6.30102999566398
P value text
Or beta
%95 Ci
PlatformIllumina [291119]
CNVN
Mapped traitAIDS
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000765
Study accessionGCST000308
PubMed ID23453885
JournalLancet
Linkwww.ncbi.nlm.nih.gov/pubmed/23453885
StudyIdentification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
Disease/TraitAutism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)
Initial sample6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder tr
Replication sampleNA
Region6p22.1
Chromosome idchr6
Chromosome position30064745
Reported geneMHC region
Mapped geneZNRD1
Upstream gene id
Downstream gene id
SNP gene ids30834
Upstream gene distance
Downstream gene distance
SNP risk allelers8321-?
SNPsrs8321
Merged0
SNP id current8321
Context3_prime_UTR_variant
Intergenic0
Allele frequencyNR
P value0.000000008
Pvalue mlog8.09691001300805
P value text(5 degree of freedom test)
Or beta1.081
%95 Ci[1.04-1.12]
PlatformNR [1252901] (imputed)
CNVN
Mapped traitattention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289
Study accessionGCST001877