SNP Detail For rs820430
1.Mapping Information
Human SNP ID rs820430
Human chromosome chr3
Human SNP position 27507409
Pig chromosome chr13
Pig SNP position 15665070
2.Annotation Information
PubMed ID25249183
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25249183
StudyGenome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
Disease/TraitSystolic blood pressure
Initial sample11,816 Han Chinese ancestry individuals
Replication sample69,146 Han Chinese ancestry individuals
Region3p24.1
Chromosome idchr3
Chromosome position27507409
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance22989
Downstream gene distance5205
SNP risk allelers820430-A
SNPsrs820430
Merged0
SNP id current820430
Contextregulatory_region_variant
Intergenic1
Allele frequency0.32
P value0.000000000001
Pvalue mlog12
P value text
Or beta0.76
%95 Ci[0.54-0.98] unit increase
PlatformAffymetrix, Illumina [2485448] (imputed)
CNVN
Mapped traitsystolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006335
Study accessionGCST002630
PubMed ID25249183
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25249183
StudyGenome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
Disease/TraitDiastolic blood pressure
Initial sample11,816 Han Chinese ancestry individuals
Replication sample69,146 Han Chinese ancestry individuals
Region3p24.1
Chromosome idchr3
Chromosome position27507409
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance22989
Downstream gene distance5205
SNP risk allelers820430-A
SNPsrs820430
Merged0
SNP id current820430
Contextregulatory_region_variant
Intergenic1
Allele frequency0.32
P value0.000008
Pvalue mlog5.09691001300805
P value text
Or beta0.27
%95 Ci[0.15-0.39] unit increase
PlatformAffymetrix, Illumina [2485448] (imputed)
CNVN
Mapped traitdiastolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006336
Study accessionGCST002631
PubMed ID25249183
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25249183
StudyGenome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
Disease/TraitHypertension
Initial sample5,065 Han Chinese ancestry cases, 4,404 Han Chinese ancestry controls
Replication sample29,799 Han Chinese ancestry cases, 39,347 Han Chinese ancestry controls
Region3p24.1
Chromosome idchr3
Chromosome position27507409
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance22989
Downstream gene distance5205
SNP risk allelers820430-A
SNPsrs820430
Merged0
SNP id current820430
Contextregulatory_region_variant
Intergenic1
Allele frequency0.32
P value0.000001
Pvalue mlog6
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [2485448] (imputed)
CNVN
Mapped traithypertension
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000537
Study accessionGCST002627