Human SNP ID | rs8192282 |
---|---|
Human chromosome | chr1 |
Human SNP position | 154429203 |
Pig chromosome | chr4 |
Pig SNP position | 104224067 |
PubMed ID | 24554482 |
---|---|
Journal | J Neurovirol |
Link | www.ncbi.nlm.nih.gov/pubmed/24554482 |
Study | Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384. |
Disease/Trait | Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) |
Initial sample | 19 European ancestry cases, 30 African American cases, 9 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls |
Replication sample | NA |
Region | 1q21.3 |
Chromosome id | chr1 |
Chromosome position | 154429203 |
Reported gene | IL6R |
Mapped gene | IL6R |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3570 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs8192282-? |
SNPs | rs8192282 |
Merged | 1 |
SNP id current | 8192282 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (Hispanic) |
Or beta | 23.2 |
%95 Ci | [NR] |
Platform | Illumina [936149] |
CNV | N |
Mapped trait | response to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100 |
Study accession | GCST002365 |