SNP Detail For rs8192282
1.Mapping Information
Human SNP ID rs8192282
Human chromosome chr1
Human SNP position 154429203
Pig chromosome chr4
Pig SNP position 104224067
2.Annotation Information
PubMed ID24554482
JournalJ Neurovirol
Linkwww.ncbi.nlm.nih.gov/pubmed/24554482
StudyGenome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Disease/TraitResponse to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy)
Initial sample19 European ancestry cases, 30 African American cases, 9 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls
Replication sampleNA
Region1q21.3
Chromosome idchr1
Chromosome position154429203
Reported geneIL6R
Mapped geneIL6R
Upstream gene id
Downstream gene id
SNP gene ids3570
Upstream gene distance
Downstream gene distance
SNP risk allelers8192282-?
SNPsrs8192282
Merged1
SNP id current8192282
Contextsynonymous_variant
Intergenic0
Allele frequency
P value0.000005
Pvalue mlog5.30102999566398
P value text(Hispanic)
Or beta23.2
%95 Ci[NR]
PlatformIllumina [936149]
CNVN
Mapped traitresponse to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100
Study accessionGCST002365