SNP Detail For rs8128234
1.Mapping Information
Human SNP ID rs8128234
Human chromosome chr21
Human SNP position 35098568
Pig chromosome chr13
Pig SNP position 208405489
2.Annotation Information
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region21q22.12
Chromosome idchr21
Chromosome position35098568
Reported geneRUNX1
Mapped geneRUNX1 - LOC100506403
Upstream gene id861
Downstream gene id100506403
SNP gene ids
Upstream gene distance49258
Downstream gene distance273939
SNP risk allelers8128234-T
SNPsrs8128234
Merged0
SNP id current8128234
Contextintron_variant
Intergenic1
Allele frequency0.197
P value0.00000006
Pvalue mlog7.22184874961635
P value text
Or beta1.13
%95 Ci[1.08-1.18]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874
PubMed ID25903422
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25903422
StudyGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
Disease/TraitPsoriasis
Initial sample3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls
Replication sample5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls
Region21q22.12
Chromosome idchr21
Chromosome position35098568
Reported geneRUNX1
Mapped geneRUNX1 - LOC100506403
Upstream gene id861
Downstream gene id100506403
SNP gene ids
Upstream gene distance49258
Downstream gene distance273939
SNP risk allelers8128234-T
SNPsrs8128234
Merged0
SNP id current8128234
Contextintron_variant
Intergenic1
Allele frequency0.197
P value0.00000004
Pvalue mlog7.39794000867203
P value textEA
Or beta1.17
%95 Ci[1.11-1.23]
PlatformIllumina [up to 4778154] (imputed)
CNVN
Mapped traitpsoriasis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000676
Study accessionGCST002874