SNP Detail For rs8112449
1.Mapping Information
Human SNP ID rs8112449
Human chromosome chr19
Human SNP position 10409388
Pig chromosome chr2
Pig SNP position 69529555
2.Annotation Information
PubMed ID21833088
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21833088
StudyGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Disease/TraitMultiple sclerosis
Initial sample9,772 European ancestry cases, 16,849 European ancestry controls
Replication sample4,218 European ancestry cases, 7,296 European ancestry controls
Region19p13.2
Chromosome idchr19
Chromosome position10409388
Reported geneCDC37, TYK2
Mapped geneCDC37 - PDE4A
Upstream gene id11140
Downstream gene id5141
SNP gene ids
Upstream gene distance5793
Downstream gene distance7385
SNP risk allelers8112449-G
SNPsrs8112449
Merged0
SNP id current8112449
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text
Or beta1.08
%95 Ci[1.07-1.1]
PlatformIllumina [465434]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001198
PubMed ID25317112
JournalGenomics Inform
Linkwww.ncbi.nlm.nih.gov/pubmed/25317112
StudyEpidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations.
Disease/TraitGastritis
Initial sample977 Korean ancestry female cases, 3,622 Korean ancestry female controls, 804 Korean ancestry male cases, 3,335 Korean ancestry male controls
Replication sampleNA
Region19p13.2
Chromosome idchr19
Chromosome position10409388
Reported geneintergenic
Mapped geneCDC37 - PDE4A
Upstream gene id11140
Downstream gene id5141
SNP gene ids
Upstream gene distance5793
Downstream gene distance7385
SNP risk allelers8112449-T
SNPsrs8112449
Merged0
SNP id current8112449
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000002
Pvalue mlog5.69897000433601
P value text(Males)
Or beta1.304
%95 Ci[NR]
PlatformNR [349184]
CNVN
Mapped traitgastritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000217
Study accessionGCST002638