Human SNP ID | rs8078723 |
---|---|
Human chromosome | chr17 |
Human SNP position | 40010626 |
Pig chromosome | chr12 |
Pig SNP position | 22797139 |
PubMed ID | 22788528 |
---|---|
Journal | Int J Immunogenet |
Link | www.ncbi.nlm.nih.gov/pubmed/22788528 |
Study | Genetic associations with C-reactive protein level and white blood cell count in the KARE study. |
Disease/Trait | C-reactive protein and white blood cell count |
Initial sample | 8,722 individuals |
Replication sample | NA |
Region | 17q21.1 |
Chromosome id | chr17 |
Chromosome position | 40010626 |
Reported gene | intergenic |
Mapped gene | PSMD3 - CSF3 |
Upstream gene id | 5709 |
Downstream gene id | 1440 |
SNP gene ids | |
Upstream gene distance | 12666 |
Downstream gene distance | 4735 |
SNP risk allele | rs8078723-C |
SNPs | rs8078723 |
Merged | 0 |
SNP id current | 8078723 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.468 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | (WBC) |
Or beta | 0.163 |
%95 Ci | [NR] 10^3/ul increase |
Platform | Affymetrix [1701735] (imputed) |
CNV | N |
Mapped trait | leukocyte count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004308 |
Study accession | GCST001605 |
PubMed ID | 21738480 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21738480 |
Study | Multiple loci are associated with white blood cell phenotypes. |
Disease/Trait | White blood cell count |
Initial sample | 19,509 European ancestry individuals |
Replication sample | 11,823 European ancestry individuals |
Region | 17q21.1 |
Chromosome id | chr17 |
Chromosome position | 40010626 |
Reported gene | CSF3, GSDMB, PSMD3, MED24, GSDMA, SNORD124, THRA, NR1D1, ORMDL3 |
Mapped gene | PSMD3 - CSF3 |
Upstream gene id | 5709 |
Downstream gene id | 1440 |
SNP gene ids | |
Upstream gene distance | 12666 |
Downstream gene distance | 4735 |
SNP risk allele | rs8078723-T |
SNPs | rs8078723 |
Merged | 0 |
SNP id current | 8078723 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | |
P value | 2E-31 |
Pvalue mlog | 30.698970004336 |
P value text | (Neutrophils) |
Or beta | 0.0407 |
%95 Ci | [0.034-0.048] unit decrease |
Platform | Affymetrix, Illumina [> 2400000] (imputed) |
CNV | N |
Mapped trait | neutrophil count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004833 |
Study accession | GCST001137 |
PubMed ID | 25096241 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25096241 |
Study | Trans-ethnic meta-analysis of white blood cell phenotypes. |
Disease/Trait | Neutrophil count |
Initial sample | 9,802 Japanese ancestry individuals, 16,550 European ancestry individuals, 7,391 African American individuals |
Replication sample | NA |
Region | 17q21.1 |
Chromosome id | chr17 |
Chromosome position | 40010626 |
Reported gene | MED24, CSF3 |
Mapped gene | PSMD3 - CSF3 |
Upstream gene id | 5709 |
Downstream gene id | 1440 |
SNP gene ids | |
Upstream gene distance | 12666 |
Downstream gene distance | 4735 |
SNP risk allele | rs8078723-C |
SNPs | rs8078723 |
Merged | 0 |
SNP id current | 8078723 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.626 |
P value | 3E-23 |
Pvalue mlog | 22.5228787452803 |
P value text | (EA) |
Or beta | 0.043 |
%95 Ci | [0.035-0.051] unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | neutrophil count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004833 |
Study accession | GCST002557 |
PubMed ID | 25096241 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25096241 |
Study | Trans-ethnic meta-analysis of white blood cell phenotypes. |
Disease/Trait | Neutrophil count |
Initial sample | 9,802 Japanese ancestry individuals, 16,550 European ancestry individuals, 7,391 African American individuals |
Replication sample | NA |
Region | 17q21.1 |
Chromosome id | chr17 |
Chromosome position | 40010626 |
Reported gene | CSF3, MED24 |
Mapped gene | PSMD3 - CSF3 |
Upstream gene id | 5709 |
Downstream gene id | 1440 |
SNP gene ids | |
Upstream gene distance | 12666 |
Downstream gene distance | 4735 |
SNP risk allele | rs8078723-C |
SNPs | rs8078723 |
Merged | 0 |
SNP id current | 8078723 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.519 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | (Japanese) |
Or beta | 0.032 |
%95 Ci | [0.022-0.042] unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | neutrophil count |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004833 |
Study accession | GCST002557 |