SNP Detail For rs7985891
1.Mapping Information
Human SNP ID rs7985891
Human chromosome chr13
Human SNP position 93226778
Pig chromosome chr11
Pig SNP position 68383456
2.Annotation Information
PubMed ID24554482
JournalJ Neurovirol
Linkwww.ncbi.nlm.nih.gov/pubmed/24554482
StudyGenome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Disease/TraitResponse to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy)
Initial sample19 European ancestry cases, 30 African American cases, 9 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls
Replication sampleNA
Region13q31.3
Chromosome idchr13
Chromosome position93226778
Reported geneGPC6
Mapped geneLINC00363 - GPC6
Upstream gene id104326053
Downstream gene id10082
SNP gene ids
Upstream gene distance168852
Downstream gene distance47
SNP risk allelers7985891-?
SNPsrs7985891
Merged0
SNP id current7985891
Contextnon_coding_transcript_exon_variant
Intergenic1
Allele frequency
P value0.0000002
Pvalue mlog6.69897000433601
P value text(EA)
Or beta38.2
%95 Ci[NR]
PlatformIllumina [936149]
CNVN
Mapped traitresponse to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100
Study accessionGCST002365