SNP Detail For rs7978454
1.Mapping Information
Human SNP ID rs7978454
Human chromosome chr12
Human SNP position 123832329
Pig chromosome chr14
Pig SNP position 30885295
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region12q24.31
Chromosome idchr12
Chromosome position123832329
Reported geneNR
Mapped geneDNAH10
Upstream gene id
Downstream gene id
SNP gene ids196385
Upstream gene distance
Downstream gene distance
SNP risk allelers7978454-G
SNPsrs7978454
Merged0
SNP id current7978454
Contextintron_variant
Intergenic0
Allele frequency0.409630410507569
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP15)
Or beta0.1473
%95 Ci[0.083-0.212] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848