Human SNP ID | rs7964748 |
---|---|
Human chromosome | chr12 |
Human SNP position | 102571551 |
Pig chromosome | chr5 |
Pig SNP position | 85607850 |
PubMed ID | 23400010 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/23400010 |
Study | Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. |
Disease/Trait | Thiazide-induced adverse metabolic effects in hypertensive patients |
Initial sample | 425 European ancestry cases, 342 African American cases |
Replication sample | NA |
Region | 12q23.2 |
Chromosome id | chr12 |
Chromosome position | 102571551 |
Reported gene | IGF1 |
Mapped gene | IGF1 - LINC00485 |
Upstream gene id | 3479 |
Downstream gene id | 283432 |
SNP gene ids | |
Upstream gene distance | 89765 |
Downstream gene distance | 237732 |
SNP risk allele | rs7964748-G |
SNPs | rs7964748 |
Merged | 0 |
SNP id current | 7964748 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.28 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (AA-glucose response) |
Or beta | 4.06 |
%95 Ci | [2.37-5.75] mg/dL increase |
Platform | Affymetrix, Illumina [> 2000000] (imputed) |
CNV | N |
Mapped trait | response to hydrochlorothiazide, fasting blood glucose measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004465 |
Study accession | GCST001859 |