Human SNP ID | rs7927894 |
---|---|
Human chromosome | chr11 |
Human SNP position | 76590272 |
Pig chromosome | chr9 |
Pig SNP position | 11854294 |
PubMed ID | 18587394 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18587394 |
Study | Genome-wide association defines more than 30 distinct susceptibility loci for Crohn__s disease. |
Disease/Trait | Crohn__s disease |
Initial sample | 3,230 European ancestry cases, 4,829 European ancestry controls |
Replication sample | 1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls |
Region | 11q13.5 |
Chromosome id | chr11 |
Chromosome position | 76590272 |
Reported gene | C11orf30 |
Mapped gene | C11orf30 - LOC101928813 |
Upstream gene id | 56946 |
Downstream gene id | 101928813 |
SNP gene ids | |
Upstream gene distance | 37373 |
Downstream gene distance | 17879 |
SNP risk allele | rs7927894-T |
SNPs | rs7927894 |
Merged | 0 |
SNP id current | 7927894 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.39 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.16 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [635547] (imputed) |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST000207 |
PubMed ID | 19349984 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19349984 |
Study | A common variant on chromosome 11q13 is associated with atopic dermatitis. |
Disease/Trait | Atopic dermatitis |
Initial sample | 939 European ancestry cases, 975 European ancestry controls, 1,097 European ancestry individuals from 270 families |
Replication sample | 2,637 European ancestry cases, 3,957 European ancestry controls |
Region | 11q13.5 |
Chromosome id | chr11 |
Chromosome position | 76590272 |
Reported gene | C11orf30 |
Mapped gene | C11orf30 - LOC101928813 |
Upstream gene id | 56946 |
Downstream gene id | 101928813 |
SNP gene ids | |
Upstream gene distance | 37373 |
Downstream gene distance | 17879 |
SNP risk allele | rs7927894-A |
SNPs | rs7927894 |
Merged | 0 |
SNP id current | 7927894 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.36 |
P value | 0.0000000008 |
Pvalue mlog | 9.09691001300805 |
P value text | |
Or beta | 1.22 |
%95 Ci | [1.15-1.30] |
Platform | Affymetrix [342303] |
CNV | N |
Mapped trait | atopic eczema |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000274 |
Study accession | GCST000374 |
PubMed ID | 26482879 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26482879 |
Study | Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. |
Disease/Trait | Atopic dermatitis |
Initial sample | 18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls |
Replication sample | 30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls |
Region | 11q13.5 |
Chromosome id | chr11 |
Chromosome position | 76590272 |
Reported gene | C11orf30 |
Mapped gene | C11orf30 - LOC101928813 |
Upstream gene id | 56946 |
Downstream gene id | 101928813 |
SNP gene ids | |
Upstream gene distance | 37373 |
Downstream gene distance | 17879 |
SNP risk allele | rs7927894-T |
SNPs | rs7927894 |
Merged | 0 |
SNP id current | 7927894 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | (EA, fixed effects) |
Or beta | 1.08 |
%95 Ci | [1.05-1.10] |
Platform | Illumina [15539996] (imputed) |
CNV | N |
Mapped trait | atopic eczema |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000274 |
Study accession | GCST003184 |