SNP Detail For rs7924176
1.Mapping Information
Human SNP ID rs7924176
Human chromosome chr10
Human SNP position 74536031
Pig chromosome chr14
Pig SNP position 83304952
2.Annotation Information
PubMed ID21931568
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21931568
StudyGenome-wide association study identifies four loci associated with eruption of permanent teeth.
Disease/TraitPermanent tooth development
Initial sample5,088 European ancestry females
Replication sample2,994 European ancestry individuals, 161 individuals
Region10q22.2
Chromosome idchr10
Chromosome position74536031
Reported geneADK
Mapped geneADK
Upstream gene id
Downstream gene id
SNP gene ids132
Upstream gene distance
Downstream gene distance
SNP risk allelers7924176-G
SNPsrs7924176
Merged0
SNP id current7924176
Contextintron_variant
Intergenic0
Allele frequency0.43
P value0.000000000000000006
Pvalue mlog17.2218487496163
P value text
Or beta0.105
%95 Ci[0.08-0.13] unit decrease
PlatformIllumina [521741]
CNVN
Mapped traittooth eruption
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0044691
Study accessionGCST001221
PubMed ID23704328
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23704328
StudyGenome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
Disease/TraitPrimary tooth development (time to first tooth eruption)
Initial sample11,118 European ancestry individuals
Replication sample
Region10q22.2
Chromosome idchr10
Chromosome position74536031
Reported geneADK, VCL, AP3M1
Mapped geneADK
Upstream gene id
Downstream gene id
SNP gene ids132
Upstream gene distance
Downstream gene distance
SNP risk allelers7924176-A
SNPsrs7924176
Merged0
SNP id current7924176
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta0.167
%95 Ci[0.11-0.22] unit decrease
PlatformIllumina [2446724] (imputed)
CNVN
Mapped traittooth eruption
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0044691
Study accessionGCST002030
PubMed ID23704328
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23704328
StudyGenome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
Disease/TraitPrimary tooth development (number of teeth)
Initial sample11,513 European ancestry individuals
Replication sample
Region10q22.2
Chromosome idchr10
Chromosome position74536031
Reported geneADK, VCL, AP3M1
Mapped geneADK
Upstream gene id
Downstream gene id
SNP gene ids132
Upstream gene distance
Downstream gene distance
SNP risk allelers7924176-A
SNPsrs7924176
Merged0
SNP id current7924176
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000000000008
Pvalue mlog15.096910013008
P value text
Or beta0.193
%95 Ci[0.15-0.24] unit increase
PlatformIllumina [2446724] (imputed)
CNVN
Mapped traitodontogenesis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0042476
Study accessionGCST002031