Human SNP ID | rs7924176 |
---|---|
Human chromosome | chr10 |
Human SNP position | 74536031 |
Pig chromosome | chr14 |
Pig SNP position | 83304952 |
PubMed ID | 21931568 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21931568 |
Study | Genome-wide association study identifies four loci associated with eruption of permanent teeth. |
Disease/Trait | Permanent tooth development |
Initial sample | 5,088 European ancestry females |
Replication sample | 2,994 European ancestry individuals, 161 individuals |
Region | 10q22.2 |
Chromosome id | chr10 |
Chromosome position | 74536031 |
Reported gene | ADK |
Mapped gene | ADK |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 132 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7924176-G |
SNPs | rs7924176 |
Merged | 0 |
SNP id current | 7924176 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.43 |
P value | 0.000000000000000006 |
Pvalue mlog | 17.2218487496163 |
P value text | |
Or beta | 0.105 |
%95 Ci | [0.08-0.13] unit decrease |
Platform | Illumina [521741] |
CNV | N |
Mapped trait | tooth eruption |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0044691 |
Study accession | GCST001221 |
PubMed ID | 23704328 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23704328 |
Study | Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. |
Disease/Trait | Primary tooth development (time to first tooth eruption) |
Initial sample | 11,118 European ancestry individuals |
Replication sample | |
Region | 10q22.2 |
Chromosome id | chr10 |
Chromosome position | 74536031 |
Reported gene | ADK, VCL, AP3M1 |
Mapped gene | ADK |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 132 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7924176-A |
SNPs | rs7924176 |
Merged | 0 |
SNP id current | 7924176 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.167 |
%95 Ci | [0.11-0.22] unit decrease |
Platform | Illumina [2446724] (imputed) |
CNV | N |
Mapped trait | tooth eruption |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0044691 |
Study accession | GCST002030 |
PubMed ID | 23704328 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23704328 |
Study | Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. |
Disease/Trait | Primary tooth development (number of teeth) |
Initial sample | 11,513 European ancestry individuals |
Replication sample | |
Region | 10q22.2 |
Chromosome id | chr10 |
Chromosome position | 74536031 |
Reported gene | ADK, VCL, AP3M1 |
Mapped gene | ADK |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 132 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7924176-A |
SNPs | rs7924176 |
Merged | 0 |
SNP id current | 7924176 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000000000000008 |
Pvalue mlog | 15.096910013008 |
P value text | |
Or beta | 0.193 |
%95 Ci | [0.15-0.24] unit increase |
Platform | Illumina [2446724] (imputed) |
CNV | N |
Mapped trait | odontogenesis |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0042476 |
Study accession | GCST002031 |