Human SNP ID | rs7920721 |
---|---|
Human chromosome | chr10 |
Human SNP position | 11678309 |
Pig chromosome | chr10 |
Pig SNP position | 65887092 |
PubMed ID | 24162737 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24162737 |
Study | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer__s disease. |
Disease/Trait | Alzheimer__s disease (late onset) |
Initial sample | 17,008 European ancestry cases, 37,154 European ancestry controls |
Replication sample | 8,572 European ancestry cases, 11,312 European ancestry controls |
Region | 10p14 |
Chromosome id | chr10 |
Chromosome position | 11678309 |
Reported gene | ECHDC3 |
Mapped gene | LOC105376413, LOC105376412 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105376413, 105376412 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7920721-G |
SNPs | rs7920721 |
Merged | 0 |
SNP id current | 7920721 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.387 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | 1.07 |
%95 Ci | [1.04-1.10] |
Platform | Illumina [7055881] (imputed) |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002245 |
PubMed ID | 25778476 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/25778476 |
Study | A novel Alzheimer disease locus located near the gene encoding tau protein. |
Disease/Trait | Alzheimer__s disease in APOE e4- carriers |
Initial sample | 7,184 cases, 26,968 controls |
Replication sample | 718 European ancestry cases, 1,699 European ancestry controls |
Region | 10p14 |
Chromosome id | chr10 |
Chromosome position | 11678309 |
Reported gene | USP6NL, ECHDC3 |
Mapped gene | LOC105376413, LOC105376412 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105376413, 105376412 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7920721-G |
SNPs | rs7920721 |
Merged | 0 |
SNP id current | 7920721 |
Context | upstream_gene_variant |
Intergenic | 0 |
Allele frequency | 0.38 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 1.12 |
%95 Ci | [1.07-1.17] |
Platform | NR [NR] |
CNV | N |
Mapped trait | Alzheimers disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249 |
Study accession | GCST002817 |