SNP Detail For rs7917772
1.Mapping Information
Human SNP ID rs7917772
Human chromosome chr10
Human SNP position 102727686
Pig chromosome chr14
Pig SNP position 123693376
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region10q24.32
Chromosome idchr10
Chromosome position102727686
Reported geneSFXN2
Mapped geneSFXN2
Upstream gene id
Downstream gene id
SNP gene ids118980
Upstream gene distance
Downstream gene distance
SNP risk allelers7917772-A
SNPsrs7917772
Merged0
SNP id current7917772
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.6194
P value0.000000006
Pvalue mlog8.22184874961635
P value text(EA, women)
Or beta0.0269
%95 Ci[0.018-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region10q24.32
Chromosome idchr10
Chromosome position102727686
Reported geneSFXN2
Mapped geneSFXN2
Upstream gene id
Downstream gene id
SNP gene ids118980
Upstream gene distance
Downstream gene distance
SNP risk allelers7917772-A
SNPsrs7917772
Merged0
SNP id current7917772
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.6186
P value0.00000002
Pvalue mlog7.69897000433601
P value text(women)
Or beta0.0251
%95 Ci[0.016-0.034] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782