SNP Detail For rs7800668
1.Mapping Information
Human SNP ID rs7800668
Human chromosome chr7
Human SNP position 117818989
Pig chromosome chr18
Pig SNP position 30245411
2.Annotation Information
PubMed ID24709693
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/24709693
StudyGenome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Disease/TraitResponse to methotrexate in juvenile idiopathic arthritis
Initial sample694 European ancestry child cases
Replication sampleNA
Region7q31.31
Chromosome idchr7
Chromosome position117818989
Reported geneLSM8, CFTR, CTTNBP2
Mapped geneCTTNBP2
Upstream gene id
Downstream gene id
SNP gene ids83992
Upstream gene distance
Downstream gene distance
SNP risk allelers7800668-C
SNPsrs7800668
Merged0
SNP id current7800668
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000006
Pvalue mlog5.22184874961635
P value text(ACR-pedi)
Or beta1.34
%95 Ci[0.75-1.93] unit decrease
PlatformIllumina [586062]
CNVN
Mapped traitresponse to methotrexate, chronic childhood arthritis
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0031427, http://www.ebi.ac.uk/efo/EFO_0002609
Study accessionGCST002408