SNP Detail For rs7776725
1.Mapping Information
Human SNP ID rs7776725
Human chromosome chr7
Human SNP position 121393067
Pig chromosome chr18
Pig SNP position 27176907
2.Annotation Information
PubMed ID19396169
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19396169
StudyA large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.
Disease/TraitBiomedical quantitative traits
Initial sample8,842 Korean ancestry individuals
Replication sample7,861 Korean ancestry individuals
Region7q31.31
Chromosome idchr7
Chromosome position121393067
Reported geneFAM3C
Mapped geneFAM3C
Upstream gene id
Downstream gene id
SNP gene ids10447
Upstream gene distance
Downstream gene distance
SNP risk allelers7776725-C
SNPsrs7776725
Merged0
SNP id current7776725
Contextintron_variant
Intergenic0
Allele frequency0.13
P value0.00000000001
Pvalue mlog11
P value text(BD-RT)
Or beta
%95 Ci
PlatformAffymetrix [2156535] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST000381
PubMed ID19396169
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19396169
StudyA large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.
Disease/TraitBiomedical quantitative traits
Initial sample8,842 Korean ancestry individuals
Replication sample7,861 Korean ancestry individuals
Region7q31.31
Chromosome idchr7
Chromosome position121393067
Reported geneFAM3C
Mapped geneFAM3C
Upstream gene id
Downstream gene id
SNP gene ids10447
Upstream gene distance
Downstream gene distance
SNP risk allelers7776725-C
SNPsrs7776725
Merged0
SNP id current7776725
Contextintron_variant
Intergenic0
Allele frequency0.13
P value0.000002
Pvalue mlog5.69897000433601
P value text(BD-TT)
Or beta
%95 Ci
PlatformAffymetrix [2156535] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST000381
PubMed ID24945404
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24945404
StudyPhenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Disease/TraitBone mineral density (paediatric, total body less head)
Initial sample8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children
Replication sampleNA
Region7q31.31
Chromosome idchr7
Chromosome position121393067
Reported geneFAM3C, WNT16, CPED1
Mapped geneFAM3C
Upstream gene id
Downstream gene id
SNP gene ids10447
Upstream gene distance
Downstream gene distance
SNP risk allelers7776725-C
SNPsrs7776725
Merged0
SNP id current7776725
Contextintron_variant
Intergenic0
Allele frequency0.27
P value6E-20
Pvalue mlog19.2218487496163
P value text
Or beta0.159
%95 Ci[0.13-0.19] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST002494
PubMed ID24945404
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24945404
StudyPhenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Disease/TraitBone mineral density (paediatric, total body less head)
Initial sample8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children
Replication sampleNA
Region7q31.31
Chromosome idchr7
Chromosome position121393067
Reported geneFAM3C, WNT16, CPED1
Mapped geneFAM3C
Upstream gene id
Downstream gene id
SNP gene ids10447
Upstream gene distance
Downstream gene distance
SNP risk allelers7776725-C
SNPsrs7776725
Merged0
SNP id current7776725
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000000000002
Pvalue mlog14.698970004336
P value text(EA)
Or beta0.1582
%95 Ci[0.12-0.2] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST002494