Human SNP ID | rs7767084 |
---|---|
Human chromosome | chr6 |
Human SNP position | 160541471 |
Pig chromosome | chr1 |
Pig SNP position | 8777419 |
PubMed ID | 19198611 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19198611 |
Study | Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. |
Disease/Trait | Coronary heart disease |
Initial sample | 1,926 European ancestry cases, 2,938 European ancestry controls |
Replication sample | 7,073 European ancestry cases, 7,325 European ancestry controls |
Region | 6q25.3 |
Chromosome id | chr6;6;6;6 |
Chromosome position | 160541471;160548706;160486102;160442500 |
Reported gene | SLC22A3, LPAL2, LPA |
Mapped gene | LPA; LPA; LPAL2; LOC105378089; SLC22A3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7767084-T; rs10755578-G; rs3127599-T; rs2048327-C |
SNPs | rs7767084; rs10755578; rs3127599; rs2048327 |
Merged | 0 |
SNP id current | |
Context | intron_variant; intron_variant; intron_variant; intron_variant |
Intergenic | |
Allele frequency | 0.16 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | |
Or beta | 1.2 |
%95 Ci | [1.13-1.28] |
Platform | Affymetrix [~ 500000] |
CNV | N |
Mapped trait | coronary heart disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001645 |
Study accession | GCST000341 |
PubMed ID | 19198611 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19198611 |
Study | Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. |
Disease/Trait | Coronary heart disease |
Initial sample | 1,926 European ancestry cases, 2,938 European ancestry controls |
Replication sample | 7,073 European ancestry cases, 7,325 European ancestry controls |
Region | 6q25.3 |
Chromosome id | chr6;6;6;6 |
Chromosome position | 160541471;160548706;160486102;160442500 |
Reported gene | SLC22A3, LPAL2, LPA |
Mapped gene | LPA; LPA; LPAL2; LOC105378089; SLC22A3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7767084-T; rs10755578-C; rs3127599-C; rs2048327-C |
SNPs | rs7767084; rs10755578; rs3127599; rs2048327 |
Merged | 0 |
SNP id current | |
Context | intron_variant; intron_variant; intron_variant; intron_variant |
Intergenic | |
Allele frequency | 0.02 |
P value | 0.000000000000004 |
Pvalue mlog | 14.397940008672 |
P value text | |
Or beta | 1.82 |
%95 Ci | [1.57-2.12] |
Platform | Affymetrix [~ 500000] |
CNV | N |
Mapped trait | coronary heart disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001645 |
Study accession | GCST000341 |