SNP Detail For rs7767084
1.Mapping Information
Human SNP ID rs7767084
Human chromosome chr6
Human SNP position 160541471
Pig chromosome chr1
Pig SNP position 8777419
2.Annotation Information
PubMed ID19198611
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19198611
StudyGenome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample1,926 European ancestry cases, 2,938 European ancestry controls
Replication sample7,073 European ancestry cases, 7,325 European ancestry controls
Region6q25.3
Chromosome idchr6;6;6;6
Chromosome position160541471;160548706;160486102;160442500
Reported geneSLC22A3, LPAL2, LPA
Mapped geneLPA; LPA; LPAL2; LOC105378089; SLC22A3
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers7767084-T; rs10755578-G; rs3127599-T; rs2048327-C
SNPsrs7767084; rs10755578; rs3127599; rs2048327
Merged0
SNP id current
Contextintron_variant; intron_variant; intron_variant; intron_variant
Intergenic
Allele frequency0.16
P value0.000000001
Pvalue mlog9
P value text
Or beta1.2
%95 Ci[1.13-1.28]
PlatformAffymetrix [~ 500000]
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000341
PubMed ID19198611
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19198611
StudyGenome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample1,926 European ancestry cases, 2,938 European ancestry controls
Replication sample7,073 European ancestry cases, 7,325 European ancestry controls
Region6q25.3
Chromosome idchr6;6;6;6
Chromosome position160541471;160548706;160486102;160442500
Reported geneSLC22A3, LPAL2, LPA
Mapped geneLPA; LPA; LPAL2; LOC105378089; SLC22A3
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers7767084-T; rs10755578-C; rs3127599-C; rs2048327-C
SNPsrs7767084; rs10755578; rs3127599; rs2048327
Merged0
SNP id current
Contextintron_variant; intron_variant; intron_variant; intron_variant
Intergenic
Allele frequency0.02
P value0.000000000000004
Pvalue mlog14.397940008672
P value text
Or beta1.82
%95 Ci[1.57-2.12]
PlatformAffymetrix [~ 500000]
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000341