SNP Detail For rs7762018
1.Mapping Information
Human SNP ID rs7762018
Human chromosome chr6
Human SNP position 169713148
Pig chromosome chr1
Pig SNP position 944527
2.Annotation Information
PubMed ID23400010
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/23400010
StudyGenome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
Disease/TraitThiazide-induced adverse metabolic effects in hypertensive patients
Initial sample425 European ancestry cases, 342 African American cases
Replication sampleNA
Region6q27
Chromosome idchr6
Chromosome position169713148
Reported geneIDDM8
Mapped genePHF10
Upstream gene id
Downstream gene id
SNP gene ids55274
Upstream gene distance
Downstream gene distance
SNP risk allelers7762018-A
SNPsrs7762018
Merged0
SNP id current7762018
Contextintron_variant
Intergenic0
Allele frequency0.13
P value0.000008
Pvalue mlog5.09691001300805
P value text(EA-glucose response)
Or beta3.65
%95 Ci[2.06-5.24] mg/dL increase
PlatformAffymetrix, Illumina [> 2000000] (imputed)
CNVN
Mapped traitresponse to hydrochlorothiazide, fasting blood glucose measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004465
Study accessionGCST001859