Human SNP ID | rs7759742 |
---|---|
Human chromosome | chr6 |
Human SNP position | 32413959 |
Pig chromosome | chr7 |
Pig SNP position | 29024099 |
PubMed ID | 25673412 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.5107 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (EA, women) |
Or beta | 0.0237 |
%95 Ci | [0.015-0.033] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.5106 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (EA, men) |
Or beta | 0.0226 |
%95 Ci | [0.013-0.032] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.511 |
P value | 0.00000000004 |
Pvalue mlog | 10.397940008672 |
P value text | (EA) |
Or beta | 0.0226 |
%95 Ci | [0.016-0.029] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.5154 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (men) |
Or beta | 0.0223 |
%95 Ci | [0.013-0.032] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.5158 |
P value | 0.00000005 |
Pvalue mlog | 7.30102999566398 |
P value text | (women) |
Or beta | 0.0241 |
%95 Ci | [0.015-0.033] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |
PubMed ID | 25673412 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/25673412 |
Study | New genetic loci link adipose and insulin biology to body fat distribution. |
Disease/Trait | Waist-to-hip ratio adjusted for body mass index |
Initial sample | up to 56,910 European ancestry men, up to 86,570 European ancestry women |
Replication sample | up to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr |
Region | 6p21.32 |
Chromosome id | chr6 |
Chromosome position | 32413959 |
Reported gene | BTNL2 |
Mapped gene | BTNL2 - HLA-DRA |
Upstream gene id | 56244 |
Downstream gene id | 3122 |
SNP gene ids | |
Upstream gene distance | 5080 |
Downstream gene distance | 25883 |
SNP risk allele | rs7759742-A |
SNPs | rs7759742 |
Merged | 0 |
SNP id current | 7759742 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.517 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 0.0224 |
%95 Ci | [0.016-0.029] unit increase |
Platform | Affymetrix, Illumina, Perlegen [up to 2542447] (imputed) |
CNV | N |
Mapped trait | waist-hip ratio, body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002782 |