SNP Detail For rs7758889
1.Mapping Information
Human SNP ID rs7758889
Human chromosome chr6
Human SNP position 138600907
Pig chromosome chr1
Pig SNP position 28963282
2.Annotation Information
PubMed ID21844884
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/21844884
StudyGenome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
Disease/TraitResponse to platinum-based chemotherapy (carboplatin)
Initial sample176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region6q24.1
Chromosome idchr6
Chromosome position138600907
Reported geneintergenic
Mapped geneNHSL1
Upstream gene id
Downstream gene id
SNP gene ids57224
Upstream gene distance
Downstream gene distance
SNP risk allelers7758889-?
SNPsrs7758889
Merged0
SNP id current7758889
Contextintron_variant
Intergenic0
Allele frequency
P value0.0000009
Pvalue mlog6.04575749056067
P value text
Or beta
%95 Ci
PlatformNR [~ 3000000] (imputed)
CNVN
Mapped traitresponse to carboplatin
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328
Study accessionGCST001204
PubMed ID21844884
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/21844884
StudyGenome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
Disease/TraitResponse to platinum-based chemotherapy (cisplatin)
Initial sample176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region6q24.1
Chromosome idchr6
Chromosome position138600907
Reported geneintergenic
Mapped geneNHSL1
Upstream gene id
Downstream gene id
SNP gene ids57224
Upstream gene distance
Downstream gene distance
SNP risk allelers7758889-?
SNPsrs7758889
Merged0
SNP id current7758889
Contextintron_variant
Intergenic0
Allele frequency
P value0.0000007
Pvalue mlog6.15490195998574
P value text
Or beta
%95 Ci
PlatformNR [~ 3000000] (imputed)
CNVN
Mapped traitresponse to cisplatin
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0072718
Study accessionGCST001201