SNP Detail For rs7758229
1.Mapping Information
Human SNP ID rs7758229
Human chromosome chr6
Human SNP position 160419220
Pig chromosome chr1
Pig SNP position 8832758
2.Annotation Information
PubMed ID21242260
JournalGut
Linkwww.ncbi.nlm.nih.gov/pubmed/21242260
StudyCommon variant in 6q26-q27 is associated with distal colon cancer in an Asian population.
Disease/TraitColorectal cancer
Initial sample1,583 Japanese ancestry cases, 1,898 Japanese ancestry controls
Replication sample4,584 Japanese ancestry cases, 225 Korean ancestry distal cases, 2,973 East Asian ancestry controls
Region6q25.3
Chromosome idchr6
Chromosome position160419220
Reported geneSLC22A3
Mapped geneSLC22A3
Upstream gene id
Downstream gene id
SNP gene ids6581
Upstream gene distance
Downstream gene distance
SNP risk allelers7758229-T
SNPsrs7758229
Merged0
SNP id current7758229
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000008
Pvalue mlog8.09691001300805
P value text(distal colon cancer)
Or beta1.28
%95 Ci[1.18-1.39]
PlatformIllumina [391749]
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST000948
PubMed ID25939597
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25939597
StudyTwo susceptibility loci identified for prostate cancer aggressiveness.
Disease/TraitProstate cancer
Initial sample4,600 European ancestry cases, 2,941 European ancestry controls
Replication sample7,779 European ancestry cases, 7,623 European ancestry controls
Region6q25.3
Chromosome idchr6
Chromosome position160419220
Reported geneSLC22A3
Mapped geneSLC22A3
Upstream gene id
Downstream gene id
SNP gene ids6581
Upstream gene distance
Downstream gene distance
SNP risk allelers7758229-T
SNPsrs7758229
Merged0
SNP id current7758229
Contextintron_variant
Intergenic0
Allele frequency0.31
P value0.000000000004
Pvalue mlog11.397940008672
P value text
Or beta1.15
%95 Ci[1.10鈥?.20]
PlatformIllumina [1531807] (imputed)
CNVN
Mapped traitprostate carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST002890