SNP Detail For rs7758080
1.Mapping Information
Human SNP ID rs7758080
Human chromosome chr6
Human SNP position 149255943
Pig chromosome chr1
Pig SNP position 18990254
2.Annotation Information
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitCrohn__s disease
Initial sample5,956 European ancestry cases, 14,927 European ancestry controls
Replication sample14,594 European ancestry cases, 26,715 European ancestry controls, 151 Iranian ancestry cases, 342 Iranian ancestry controls, 184 Indian ancestry cases, 990 Indian ancestry controls, 1,690 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region6q25.1
Chromosome idchr6
Chromosome position149255943
Reported geneMAP3K7IP2
Mapped geneLOC105378049, TAB2
Upstream gene id
Downstream gene id
SNP gene ids105378049, 23118
Upstream gene distance
Downstream gene distance
SNP risk allelers7758080-G
SNPsrs7758080
Merged
SNP id current7758080
Contextintron_variant
Intergenic0
Allele frequency0.2694
P value0.000000007
Pvalue mlog8.15490195998574
P value text(EA)
Or beta1.0790637
%95 Ci[1.05-1.1]
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST003044
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitInflammatory bowel disease
Initial sample12,882 European ancestry cases, 21,770 European ancestry controls
Replication sample25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region6q25.1
Chromosome idchr6
Chromosome position149255943
Reported geneMAP3K7IP2
Mapped geneLOC105378049, TAB2
Upstream gene id
Downstream gene id
SNP gene ids105378049, 23118
Upstream gene distance
Downstream gene distance
SNP risk allelers7758080-G
SNPsrs7758080
Merged
SNP id current7758080
Contextintron_variant
Intergenic0
Allele frequency0.2694
P value0.0000001
Pvalue mlog7
P value text(EA)
Or beta1.0597305
%95 Ci[1.04-1.08]
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitinflammatory bowel disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003767
Study accessionGCST003043