Human SNP ID | rs7754840 |
---|---|
Human chromosome | chr6 |
Human SNP position | 20661019 |
Pig chromosome | chr7 |
Pig SNP position | 16933777 |
PubMed ID | 17463246 |
---|---|
Journal | Science |
Link | www.ncbi.nlm.nih.gov/pubmed/17463246 |
Study | Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. |
Disease/Trait | Type 2 diabetes |
Initial sample | 1,464 European ancestry cases, 1,467 European ancestry controls |
Replication sample | 5,065 European ancestry cases, 5,785 European ancestry controls |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 20661019 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54901 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7754840-C |
SNPs | rs7754840 |
Merged | 0 |
SNP id current | 7754840 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.31 |
P value | 0.00000000004 |
Pvalue mlog | 10.397940008672 |
P value text | (DGI+FUSION+WTCCC) |
Or beta | 1.12 |
%95 Ci | [1.08-1.16] |
Platform | Affymetrix [386731] |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST000028 |
PubMed ID | 17463248 |
Journal | Science |
Link | www.ncbi.nlm.nih.gov/pubmed/17463248 |
Study | A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. |
Disease/Trait | Type 2 diabetes |
Initial sample | 1,161 European ancestry cases, 1,174 European ancestry controls |
Replication sample | 1,215 European ancestry cases, 1,258 European ancestry controls |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 20661019 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54901 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7754840-C |
SNPs | rs7754840 |
Merged | 0 |
SNP id current | 7754840 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.36 |
P value | 0.00000000004 |
Pvalue mlog | 10.397940008672 |
P value text | (DGI+FUSION+WTCCC) |
Or beta | 1.12 |
%95 Ci | [1.08-1.16] |
Platform | Illumina [315635] |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST000024 |
PubMed ID | 22233651 |
Journal | Diabetes |
Link | www.ncbi.nlm.nih.gov/pubmed/22233651 |
Study | A genome-wide association study of gestational diabetes mellitus in Korean women. |
Disease/Trait | Diabetes (gestational) |
Initial sample | 468 Korean ancestry cases, 1,242 Korean ancestry controls |
Replication sample | 931 Korean ancestry cases, 783 Korean ancestry controls |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 20661019 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54901 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7754840-C |
SNPs | rs7754840 |
Merged | 0 |
SNP id current | 7754840 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.445 |
P value | 0.0000000000000007 |
Pvalue mlog | 15.1549019599857 |
P value text | |
Or beta | 1.518 |
%95 Ci | [1.372-1.680] |
Platform | Affymetrix [2188613] (imputed) |
CNV | N |
Mapped trait | gestational diabetes |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004593 |
Study accession | GCST001375 |
PubMed ID | 22961080 |
Journal | Diabetes |
Link | www.ncbi.nlm.nih.gov/pubmed/22961080 |
Study | A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. |
Disease/Trait | Type 2 diabetes |
Initial sample | 1,839 Han Chinese ancestry cases, 1,873 Han Chinese ancestry controls |
Replication sample | 15,979 East Asian ancestry cases, 19,360 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 20661019 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54901 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7754840-C |
SNPs | rs7754840 |
Merged | 0 |
SNP id current | 7754840 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.411 |
P value | 0.0000000007 |
Pvalue mlog | 9.15490195998574 |
P value text | |
Or beta | 1.35 |
%95 Ci | [1.23-1.48] |
Platform | Illumina [2234194] (imputed) |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST001666 |
PubMed ID | 23945395 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23945395 |
Study | Genome-wide association study identifies three novel loci for type 2 diabetes. |
Disease/Trait | Type 2 diabetes |
Initial sample | 5,976 Japanese ancestry cases, 20,829 Japanese ancestry controls |
Replication sample | 24,416 East Asian ancestry cases, 13,985 East Asian ancestry controls |
Region | 6p22.3 |
Chromosome id | chr6 |
Chromosome position | 20661019 |
Reported gene | CDKAL1 |
Mapped gene | CDKAL1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54901 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7754840-C |
SNPs | rs7754840 |
Merged | 0 |
SNP id current | 7754840 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.42 |
P value | 0.0000000000002 |
Pvalue mlog | 12.698970004336 |
P value text | |
Or beta | 1.18 |
%95 Ci | [1.13-1.23] |
Platform | Illumina [6209637] (imputed) |
CNV | N |
Mapped trait | type II diabetes mellitus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001360 |
Study accession | GCST002128 |