SNP Detail For rs77542162
1.Mapping Information
Human SNP ID rs77542162
Human chromosome chr17
Human SNP position 69085137
Pig chromosome JH118785-1
Pig SNP position 19629
2.Annotation Information
PubMed ID25961943
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25961943
StudyThe impact of low-frequency and rare variants on lipid levels.
Disease/TraitCholesterol, total
Initial sampleup to 62,166 European ancestry individuals
Replication sampleNA
Region17q24.2
Chromosome idchr17
Chromosome position69085137
Reported geneABCA6, ABCA68
Mapped geneABCA6
Upstream gene id
Downstream gene id
SNP gene ids23460
Upstream gene distance
Downstream gene distance
SNP risk allelers77542162-G
SNPsrs77542162
Merged
SNP id current77542162
Contextmissense_variant
Intergenic0
Allele frequency0.02
P value0.0000000000002
Pvalue mlog12.698970004336
P value text
Or beta0.179
%95 Ci[0.13-0.23] s.d. increase
PlatformAffymetrix, Illumina, Perlegen [up to 9657952] (imputed)
CNVN
Mapped traittotal cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004574
Study accessionGCST002896
PubMed ID25961943
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25961943
StudyThe impact of low-frequency and rare variants on lipid levels.
Disease/TraitLDL cholesterol
Initial sampleup 62,166 European ancestry individuals
Replication sampleNA
Region17q24.2
Chromosome idchr17
Chromosome position69085137
Reported geneABCA6, ABCA8
Mapped geneABCA6
Upstream gene id
Downstream gene id
SNP gene ids23460
Upstream gene distance
Downstream gene distance
SNP risk allelers77542162-G
SNPsrs77542162
Merged
SNP id current77542162
Contextmissense_variant
Intergenic0
Allele frequency0.02
P value0.000000000000000002
Pvalue mlog17.698970004336
P value text
Or beta0.22
%95 Ci[0.17-0.27] s.d. increase
PlatformAffymetrix, Illumina, Perlegen [up to 9657952] (imputed)
CNVN
Mapped traitlow density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004611
Study accessionGCST002898